Remineralization effects of conventional and experimental ion-releasing materials in chemically or bacterially-induced dentin caries lesions

Schwendicke, Falk; Al-Abdi, Allam; Moscardó, Agustín Pascual; Cascales, Álvaro Ferrando; Sauro, Salvatore

doi:10.1016/j.dental.2019.02.021

Cited by 54 publications

(34 citation statements)

References 34 publications

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“…The pH change of distilled water in contact with BR and CS sealers was evaluated. Alkaline pH plays a key role as it may enhance the antibacterial activity of a material [ 37 ], improve the healing process, neutralize the lactic acid from the osteoclast [ 46 , 47 ], and increases the deposition of mineralized components [ 48 ]. The current study showed that both BR and CS increased the pH of the storage media ( Figure 4 ).…”

Section: Discussionmentioning

confidence: 99%

Physicochemical and Antibacterial Properties of Novel, Premixed Calcium Silicate-Based Sealer Compared to Powder–Liquid Bioceramic Sealer

Kharouf

Arntz

Eid

et al. 2020

JCM

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The aim of this study was to compare the physicochemical properties, filling ability, and antibacterial activity of a premixed calcium silicate-based sealer to those of a powder–liquid bioceramic sealer. Ceraseal (CS) and BioRoot (BR) materials were analyzed using scanning electron microscopy and energy-dispersive X-ray spectroscopy at 7 and 14 d of immersion in distilled water. The filling ability of the two sealers as well as the water contact angle, solubility, flow, roughness, crystalline microstructure, pH, and compressive strength were also evaluated. The antibacterial activity was assessed through an agar diffusion as well as through direct tests. All the results were statistically analyzed using one-way or two-way analysis of variance tests. Statistically significant lower void percentages were observed for CS at 2 and 8 mm from the working length (WL) compared to those for the BR group, whilst no significant difference was observed at 5 mm from the WL. BR sealer showed higher alkaline pH, rougher surface, lower water contact angle values, lower flowability, and higher solubility compared to CS. BR showed globular and needle-like crystalline microstructure, whilst CS had globular and flower-like crystalline microstructure up to 72 h. No statistical difference was found for the compressive strength between the two sealers. BR and CS showed no antibacterial effect against Enterococcus faecalis after 3 h, whilst both sealers showed antibacterial capacity after 24 and 72 h. BR demonstrated higher antibacterial activity after 24 h. In conclusion, the use of bioceramic sealers may play an important role in controlling bacterial growth. Moreover, CS may have superior filling ability and lower solubility than the BioRoot sealer due to its specific chemical composition and mixing method.

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Section: Discussionmentioning

confidence: 99%

Physicochemical and Antibacterial Properties of Novel, Premixed Calcium Silicate-Based Sealer Compared to Powder–Liquid Bioceramic Sealer

Kharouf

Arntz

Eid

et al. 2020

JCM

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“…46 C significant visual differences were reported between control and test groups at t3. e remineralizing properties of biomimetic nano-hydroxyapatite are particularly useful for patients with high risk of enamel demineralization, which can be linked with greater possibility of carious lesions [31]. In fact, this treatment could be useful in patients with higher caries risk, such as orthodontic patients.…”

Section: Discussionmentioning

confidence: 99%

Biomimetic Effect of Nano-Hydroxyapatite in Demineralized Enamel before Orthodontic Bonding of Brackets and Attachments: Visual, Adhesion Strength, and Hardness in In Vitro Tests

Scribante

Farahani

Marino

et al. 2020

BioMed Research International

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Dietary habits with high consumption of acidic food can induce in orthodontic patients an increased risk of demineralization lesions around orthodontic brackets and bands. The purpose of the present laboratory study is to assess the in vitro visual efficacy of a biomimetic nano-hydroxyapatite remineralizing solution in a hypomineralized enamel surface and its effect on adhesion of fixed orthodontic appliances and on enamel microhardness. Intact teeth were demineralized, and subsequently the areas of demineralization were visually recorded using a 0–100 scale. Subsequently, a remineralizing solution (Biorepair® Repair Shock Treatment) was applied for ten minutes once a day/for one week per month for a total remineralizing treatment of 3 months. Visual effects were recorded. Moreover, bond strength was recorded and adhesive remnant index scores were measured for both orthodontic brackets and composite attachments both before demineralization and after demineralization and application of remineralizing solution. Also, Vickers microhardness was measured. All data were submitted to statistical analysis. The application of remineralizing solution induced a significant in vitro reduction of demineralized areas after the first week of application. No significant differences between untreated enamel surfaces and remineralized surfaces were detected after 2 months of remineralizing treatment. Bond strength values were significantly reduced for both brackets and attachments after remineralizing treatment. However, attachments showed higher adhesion values than brackets in both conditions tested. Remineralized enamel showed significantly higher microhardness values than demineralized enamel and lower values than intact enamel.

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“…Biomimetic non-collagen analogs and molecules are generally used for remineralization of dentin. The commonly used biomimetic molecules include casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), bioglass, polyacrylic acid (PAA), synthetic polypeptide and polyamide-amine dendrimer (PAMAM) [11][12][13][14].…”

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confidence: 99%

Remineralization of dentin slices using casein phosphopeptide–amorphous calcium phosphate combined with sodium tripolyphosphate

Zhou

Bian

et al. 2020

BioMed Eng OnLine

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Background Dentin hypersensitivity is a commonly found symptom in stomatology and it is usually caused by loss of enamel and demineralization of dentin leading to symptoms of sore teeth following dentin irritation [1]. The worldwide prevalence of dentin hypersensitivity ranges from 8 to 74% worldwide [2-4]. Dentin hypersensitivity can be treated with nerve stabilization or with potassium and dental laser irradiation

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Remineralization effects of conventional and experimental ion-releasing materials in chemically or bacterially-induced dentin caries lesions

Cited by 54 publications

References 34 publications

Physicochemical and Antibacterial Properties of Novel, Premixed Calcium Silicate-Based Sealer Compared to Powder–Liquid Bioceramic Sealer

Physicochemical and Antibacterial Properties of Novel, Premixed Calcium Silicate-Based Sealer Compared to Powder–Liquid Bioceramic Sealer

Biomimetic Effect of Nano-Hydroxyapatite in Demineralized Enamel before Orthodontic Bonding of Brackets and Attachments: Visual, Adhesion Strength, and Hardness in In Vitro Tests

Remineralization of dentin slices using casein phosphopeptide–amorphous calcium phosphate combined with sodium tripolyphosphate

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