The aim of study was to compare the clinical effectiveness of 810nm laser therapy, remineralising therapy with MI PASTE PLUS� (GC), and toothbrush with Sensodyne� Repair&Protect (GSK) in cervical dentine hypersensitivity. The study was performed on 60 subjects (34 females, 24 males), with at least one tooth affected by cervical dentine hypersensitivity. The patients were randomly divided in three study groups (20 subjects for each group), related to the type of desensitizing therapy: 810nm laser therapy, remineralising therapy with gel MI PASTE PLUS�, toothbrushing with Sensodyne� Repair&Protect). The assessment of the therapy effectiveness was performed by analysis of Schiff Cold Air Sensitivity Scale, with scores directly related to the level of dentine hypersensitivity. For laser group the scores decreased from 2.25 at baseline, at 1.35 at 3 days, and 0.2 at 7 days, with significant statistical differences at 3 days, and 7 days comparing with baseline. For MI PASTE PLUS� (GC) study group the scores decreased from 2.20 at baseline, at 1.60 at 3 days, and 1.30 at 7 days, with significant statistical differences at 3 days, and 7 days comparing with baseline. For Sensodyne� Repair&Protect (GSK) study group the scores decreased from 2.15 at baseline, at 1.90 at 3 days, and 1.45 at 7 days, with significant statistical differences at 3 days, and 7 days comparing with baseline. Low level laser therapy showed better reduction in cervical hypersensitivity, followed by the therapy using MI PASTE PLUS� (GC) gel, and by the toothbrush with Sensodyne� Repair&Protect (GSK) toothpaste.