Remission of metabolic syndrome following a 15-week low-calorie lifestyle change program for weight loss

Abstract

Objective: To evaluate the rate of remission of metabolic syndrome (Met Syn) among patients undergoing a brief, low-calorie lifestyle change weight loss intervention and to compare the baseline characteristics of patients who were remitted and not remitted from Met Syn at post-treatment. Research Methods and Procedures: Obese adults (N ¼ 36) meeting criteria for Met Syn enrolled in an outpatient fee-forservice behavioral weight loss intervention. Participants were assessed on key Met Syn variables (waist circumference, blood pressure, triglycerides, high-density lipoprotein (HDL) cholesterol and fasting blood glucose) at pre-and post-treatment. Results: The majority of patients (61%) responded to treatment after a 9.9% mean weight loss. Although Met Syn responders did not differ significantly from Met Syn non-responders on any baseline Met Syn criterion variable, responders had significantly lower baseline body mass indices (BMI; kg/m 2 ) and met criteria for fewer baseline Met Syn variables. As expected, Met Syn responders, compared with Met Syn non-responders, had significantly lower post-treatment waist circumference, systolic and diastolic blood pressures, triglycerides and fasting blood glucose. Patient groups did not differ significantly on weight lost (kg or %), or on the proportion of patients losing X10% of initial body weight. Discussion: In a community population, Met Syn responds to weight loss through a low-calorie lifestyle intervention; for some patients, however, the recommended 10% weight loss may not be enough for Met Syn remission.

‘Red Ruby’: an interactive web-based intervention for lifestyle modification on metabolic syndrome: a study protocol for a randomized controlled trial

“…Recent evidence support that lifestyle interventions including physical activity and low-calorie diet might lead to at least 10% weight loss [88]. …”

Reading nutrition labels is associated with a lower risk of metabolic syndrome in Korean adults: The 2007–2008 Korean NHANES

“…Although the leading cause and pathophysiology of MetS is not yet clearly understood, socioeconomic status and dietary pattern have been shown to play important roles in the development and progression of MetS [17,18]. In particular, socioeconomic status such as household income seems to lead to two different food consumption patterns in developing and developed countries.…”

“…The prevalence of MetS in adult populations varies from 20% to 30% depending on age, ethnicity, and diagnostic criteria, but has rapidly increased in recent decades [16]. Although its pathophysiology is not completely understood, low socioeconomic status and high caloric intake are important risk factors for MetS [17,18]. That said, there is little evidence that awareness of nutrition labels is associated with MetS independently of caloric intake and socioeconomic status.…”

Feasibility of an Internet Physical Activity Intervention

“…Diet changes were not addressed because of the feasibility of introducing two different behaviors for change in a limited time frame. Recent evidence supports lifestyle changes, including physical activity and diet, to achieve at least 10% weight loss for remission of metabolic syndrome (Lundgren, Malcolm, Binks, & Oneil, 2009). For most individuals, diet is a necessary adjunct to physical activity to improve metabolic syndrome and is feasible in a staged intervention approach.…”