Remote Effects of Non-Invasive Cerebellar Stimulation on Error Processing in Motor Re-Learning

Taubert, Marco; Stein, Thorsten; Kreutzberg, Tommy; Stockinger, C.; Hecker, Lukas; Focke, Anne; Ragert, Patrick; Villringer, Arno; Pleger, Burkhard

doi:10.1016/j.brs.2016.04.007

Cited by 17 publications

(35 citation statements)

References 58 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Concerning this matter, we believe our tDCS paradigm to be consistent with most studies examining tDCS-induced muscle strength modulations [8]. Stimulation sites of both M1-tDCS, as well as CB-tDCS, were chosen based on common directives from recent literature [8,38,44]. We selected a current of 2 mA, as it has been reported that a current of 2 mA penetrates deeper through the skull when compared to 1.5 mA or 1 mA [48] and is commonly employed when administering tDCS over CB or M1.…”

Section: Discussionmentioning

confidence: 95%

See 1 more Smart Citation

Cerebellar Transcranial Direct Current Stimulation Improves Maximum Isometric Force Production during Isometric Barbell Squats

Kenville

Maudrich

et al. 2020

Brain Sciences

Self Cite

View full text Add to dashboard Cite

Maximum voluntary contraction force (MVC) is an important predictor of athletic performance as well as physical fitness throughout life. Many everyday life activities involve multi-joint or whole-body movements that are determined in part through optimized muscle strength. Transcranial direct current stimulation (tDCS) has been reported to enhance muscle strength parameters in single-joint movements after its application to motor cortical areas, although tDCS effects on maximum isometric voluntary contraction force (MIVC) in compound movements remain to be investigated. Here, we tested whether anodal tDCS and/or sham stimulation over primary motor cortex (M1) and cerebellum (CB) improves MIVC during isometric barbell squats (iBS). Our results provide novel evidence that CB stimulation enhances MIVC during iBS. Although this indicates that parameters relating to muscle strength can be modulated through anodal tDCS of the cerebellum, our results serve as an initial reference point and need to be extended. Therefore, further studies are necessary to expand knowledge in this area of research through the inclusion of different tDCS paradigms, for example investigating dynamic barbell squats, as well as testing other whole-body movements.

show abstract

Section: Discussionmentioning

confidence: 95%

“…For anodal tDCS of M1, we placed the anode 1 cm behind the vertex (Cz) on the mid-sagittal line to cover both leg motor cortices. For anodal cerebellar stimulation, the anode was placed 2 cm below the inion [38,44]. During SH-tDCS, a 2 mA current was maintained for 30 s before being ramped down and terminated.…”

Section: Transcranial Direct Current Stimulationmentioning

confidence: 99%

Cerebellar Transcranial Direct Current Stimulation Improves Maximum Isometric Force Production during Isometric Barbell Squats

Kenville

Maudrich

et al. 2020

Brain Sciences

Self Cite

View full text Add to dashboard Cite

show abstract

“…This study also showed that cerebellar ctDCS delayed the feedback response to the introduced perturbation and decreased the learning rate. Taubert et al (2016) observed impaired adaptation and re-acquisition of a force-field perturbation with cerebellar atDCS, while no effect was found for ctDCS. It is possible that the experimental design differences of these studies may explain the inconsistent findings.…”

Section: Modulating Motor Learning Processes Through Tdcsmentioning

confidence: 99%

Modulating Motor Learning through Transcranial Direct-Current Stimulation: An Integrative View

2016

View full text Add to dashboard Cite

Motor learning consists of the ability to improve motor actions through practice playing a major role in the acquisition of skills required for high-performance sports or motor function recovery after brain lesions. During the last decades, it has been reported that transcranial direct-current stimulation (tDCS), consisting in applying weak direct current through the scalp, is able of inducing polarity-specific changes in the excitability of cortical neurons. This low-cost, painless and well-tolerated portable technique has found a wide-spread use in the motor learning domain where it has been successfully applied to enhance motor learning in healthy individuals and for motor recovery after brain lesion as well as in pathological states associated to motor deficits. The main objective of this mini-review is to offer an integrative view about the potential use of tDCS for human motor learning modulation. Furthermore, we introduce the basic mechanisms underlying immediate and long-term effects associated to tDCS along with important considerations about its limitations and progression in recent years.

show abstract

“…This may render motor adaptation tasks subject to ceiling effects in healthy individuals. Differential anodal ctDCS effects with respect to task characteristics have also been noted following a single session of anodal ctDCS where stimulation enhanced gains in motor performance measured up to 48 h after the intervention in motor skill learning 9 , 10 but not motor adaptation paradigms 46 , 47 . The cerebellum’s contribution to motor learning is to a large extent dependent on error-based learning; repeated exposure to the same adaptation task may provide an insufficient stimulus to evoke a cerebellar contribution to motor learning 48 .…”

Section: Discussionmentioning

confidence: 88%

Cerebellar transcranial direct current stimulation for learning a novel split-belt treadmill task: a randomised controlled trial

Kumari

Taylor

Rashid

et al. 2020

Sci Rep

View full text Add to dashboard Cite

This study aimed to examine the effect of repeated anodal cerebellar transcranial direct current stimulation (ctDcS) on learning a split-belt treadmill task. thirty healthy individuals randomly received three consecutive sessions of active or sham anodal ctDcS during split-belt treadmill training. Motor performance and strides to steady-state performance were evaluated before (baseline), during (adaptation), and after (de-adaptation) the intervention. the outcomes were measured one week later to assess absolute learning and during the intervention to evaluate cumulative, consecutive, and session-specific effects. Data were analysed using linear mixed-effects regression models. During adaptation, there was no significant difference in absolute learning between the groups (p > 0.05). During de-adaptation, a significant difference in absolute learning between the groups (p = 0.03) indicated slower de-adaptation with anodal ctDcS. pre-planned secondary analysis revealed that anodal ctDCS significantly reduced the cumulative (p = 0.01) and consecutive-session effect (p = 0.01) on immediate adaptation. There were significant cumulative (p = 0.02) and session-specific effects (p = 0.003) on immediate de-adaptation. Repeated anodal ctDCS does not enhance motor learning measured during adaptation to a split-belt treadmill task. However, it influences the maintenance of learnt walking patterns, suggesting that it may be beneficial in maintaining therapeutic effects. Cerebellar transcranial direct current stimulation (ctDCS), a non-invasive brain stimulation technique, has the potential to become a neuro-rehabilitation tool to facilitate therapy-induced recovery in people with brain lesions 1,2. Various neuro-physiological studies 3-5 have demonstrated that ctDCS is capable of altering the excitability of the cerebellum, a critical structure in error-driven motor learning 6-8. There is evidence of improved gains in motor performance up to 48 h after a single application of anodal ctDCS 9,10. However, evidence of its ability to induce long-lasting changes in motor performance with multiple sessions of stimulation is limited 11,12. This study aimed to elucidate the effect of three consecutive sessions of anodal ctDCS on motor learning of a novel treadmill walking task in healthy individuals. Motor learning is an internal process associated with practice or experience, which results in the long-lasting acquisition of skilled motor performance 13. To examine the effect of an intervention on motor learning, evaluation of motor performance more than 24 h after the intervention is required 13. This is because the transient effects of the intervention dissipate, but the relatively permanent effects remain at the follow-up evaluation reflecting learning. Such learning is fundamental for acquiring new motor skills and adapting to changing environments in our daily lives. Motor learning is commonly investigated in the laboratory through motor skill and motor adaptation paradigms. Motor skill training paradigms often use novel or compl...

show abstract

Remote Effects of Non-Invasive Cerebellar Stimulation on Error Processing in Motor Re-Learning

Cited by 17 publications

References 58 publications

Cerebellar Transcranial Direct Current Stimulation Improves Maximum Isometric Force Production during Isometric Barbell Squats

Cerebellar Transcranial Direct Current Stimulation Improves Maximum Isometric Force Production during Isometric Barbell Squats

Modulating Motor Learning through Transcranial Direct-Current Stimulation: An Integrative View

Cerebellar transcranial direct current stimulation for learning a novel split-belt treadmill task: a randomised controlled trial

Contact Info

Product

Resources

About