Removal of antibiotics and antibiotic resistance genes from domestic sewage by constructed wetlands: Effect of flow configuration and plant species

Chen, Jun; Ying, Guang‐Guo; Wei, Xiaodong; Liu, You-Sheng; Liu, Shuangshuang; Hu, Li‐Xin; He, Liang-Ying; Chen, Zhifeng; Chen, Fanrong; Yang, Yongqiang

doi:10.1016/j.scitotenv.2016.07.085

Cited by 179 publications

(64 citation statements)

References 64 publications

(78 reference statements)

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“…In another study, six mesocosm-scale constructed wetland with three flow types (surface flow, horizontal subsurface flow, and vertical subsurface flow) were set up. Based on this study, sul (1) , sul (2) , sul (3) , tet (G), tet (M), tet (O), tet (X), erm (B), erm (C), cml (A) and flo (R) were observed in the wetlands (Chen et al, 2016 ).…”

Section: Introductionmentioning

confidence: 70%

“…These characteristics are namely, flow configuration, plant species and flow types including (surface flow, horizontal subsurface flow, and vertical subsurface flow). Biodegradation, substrate adsorption, and plant uptake all play a certain role in decreasing the loadings of nutrients, antibiotics, and ARGs in the constructed wetlands, however, biodegradation is the most vital process in the removal of these pollutants (Chen et al, 2016 ).…”

Section: Treatment Strategiesmentioning

confidence: 99%

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Strategies to Combat Antibiotic Resistance in the Wastewater Treatment Plants

2018

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The main goal of this manuscript is to review different treatment strategies and mechanisms for combating the antibiotic resistant bacteria (ARB) and antibiotic resistant genes (ARGs) in the wastewater environment. The high amount of antibiotics is released into the wastewater that may promote selection of ARB and ARGs which find their way into natural environments. Emerging microbial pathogens and increasing antibiotic resistance among them is a global public health issue. The propagation and spread of ARB and ARGs in the environment may result in an increase of antibiotic resistant microbial pathogens which is a worldwide environmental and public health concern. A proper treatment of wastewater is essential before its discharge into rivers, lake, or sewage system to prevent the spread of ARB and ARGs into the environment. This review discusses various treatment options applied for combating the spread of ARB and ARGs in wastewater treatment plants (WWTPs). It was reported that low-energy anaerobic–aerobic treatment reactors, constructed wetlands, and disinfection processes have shown good removal efficiencies. Nanomaterials and biochar combined with other treatment methods and coagulation process are very recent strategies regarding ARB and ARGs removal and need more investigation and research. Based on current studies a wide-ranging removal efficiency of ARGs can be achieved depending on the type of genes present and treatment processes used, still, there are gaps that need to be further investigated. In order to find solutions to control dissemination of antibiotic resistance in the environment, it is important to (1) study innovative strategies in large scale and over a long time to reach an actual evaluation, (2) develop risk assessment studies to precisely understand occurrence and abundance of ARB/ARGs so that their potential risks to human health can be determined, and (3) consider operating and environmental factors that affect the efficiency of each treatment mechanism.

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Section: Introductionmentioning

confidence: 70%

Section: Treatment Strategiesmentioning

confidence: 99%

Strategies to Combat Antibiotic Resistance in the Wastewater Treatment Plants

2018

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“…Sediments within sanitation wetland/pond systems and receiving water sediments may be "hot-spots" for AMR development (Cummings et al, 2011), due to increased microbial activity and influx of wastewater-borne ARGs compared to free-waters above. Nonetheless, constructed wetlands have been shown to effectively reduce ARGs (log 10 reductions of 0.26-3.3) and antimicrobials Chen et al, 2016) and thus could provide a net protective effect prior to effluent reuse applications in agriculture. (sul1, sul2, sul3, tetA, tetB, tetC, tetE, tetH, tetM, tetO, tetW, qnrS, qnrB, qepA) 8 (sul1, sul2, sul3, tetA, tetB, tetC, tetE, tetH, tetM, tetO, tetW, qnrS, qnrB, qepA) While conventional WWTPs do not appear to reduce the (normalized) integron copy number, they do reduce the diversity of gene cassette arrays measured in the raw wastewater (Stalder et al, 2014), the plasmid resistome (Szczepanowski et al, 2009), and ARGs generally by some 33-98% (Tao et al, 2014).…”

Section: Wetland/pond Sanitation Systemsmentioning

confidence: 99%

Antimicrobal Resistance: Fecal Sanitation Strategies for Combatting a Global Public Health Threat

Ashbolt¹,

Pruden²,

Miller³

et al. 2019

Water and Sanitation for the 21st Century: Health and Microbiological Aspects of Excreta and Wastewater Management (Global Wate

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“…Previous reports also showed that the adsorption process only accounted for a minor percentage of the total removal in CWs [12].…”

Section: Introductionmentioning

confidence: 90%

“…ARGs could be spread through horizontal gene transfer (HGT) and vertical gene transfer (VGT), and in many cases, could be maintained in microbial populations, even without selection pressure from antibiotics [9][10][11]. HGT is a major pathway for the transfer of ARGs, including conjugative transposons, integrons, insertion sequences, and plasmids [11,12]. ARGs have often been detected as part of antibiotic resistance super integrons.…”

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confidence: 99%

Constructed Wetland Revealed Efficient Sulfamethoxazole Removal but Enhanced the Spread of Antibiotic Resistance Genes

Zhang

et al. 2020

Molecules

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Constructed wetlands (CWs) could achieve high removal efficiency of antibiotics, but probably stimulate the spread of antibiotic resistance genes (ARGs). In this study, four CWs were established to treat synthetic wastewater containing sulfamethoxazole (SMX). SMX elimination efficiencies, SMX degradation mechanisms, dynamic fates of ARGs, and bacterial communities were evaluated during the treatment period (360 day). Throughout the whole study, the concentration of SMX in the effluent gradually increased (p < 0.05), but in general, the removal efficiency of SMX remained at a very high level (>98%). In addition, the concentration of SMX in the bottom layer was higher compared with that in the surface layer. The main byproducts of SMX degradation were found to be 4-amino benzene sulfinic acid, 3-amino-5-methylisoxazole, benzenethiol, and 3-hydroxybutan-1-aminium. Temporally speaking, an obvious increase of sul genes was observed, along with the increase of SMX concentration in the bottom and middle layers of CWs. Spatially speaking, the concentration of sul genes increased from the surface layer to the bottom layer.

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Removal of antibiotics and antibiotic resistance genes from domestic sewage by constructed wetlands: Effect of flow configuration and plant species

Cited by 179 publications

References 64 publications

Strategies to Combat Antibiotic Resistance in the Wastewater Treatment Plants

Strategies to Combat Antibiotic Resistance in the Wastewater Treatment Plants

Antimicrobal Resistance: Fecal Sanitation Strategies for Combatting a Global Public Health Threat

Constructed Wetland Revealed Efficient Sulfamethoxazole Removal but Enhanced the Spread of Antibiotic Resistance Genes

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