Removing human immunodeficiency virus (HIV) from human blood using immobilized heparin

Nassar, Roger A.; Browne, Edward P.; Chen, Jianzhu; Klibanov, Alexander M.

doi:10.1007/s10529-011-0840-0

Cited by 20 publications

(10 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Viruses. Heparin affinity chromatography can be used to purify several viruses from complex biologic media, including hepatitis B and C (Zahn and Allain, 2005), human papilloma virus (HPV) (Kim et al, 2012), porcine reproductive and respiratory syndrome virus , and lentiviruses (Segura et al, 2010), including human immunodeficiency virus HIV-1 (Nassar et al, 2012), as recent examples.…”

Section: G Interactions Between Heparin and Pathogensmentioning

confidence: 99%

Pharmacology of Heparin and Related Drugs

et al. 2015

View full text Add to dashboard Cite

Section: G Interactions Between Heparin and Pathogensmentioning

confidence: 99%

Pharmacology of Heparin and Related Drugs

et al. 2015

View full text Add to dashboard Cite

“…In the search for alternatives, some attempts have been made by researchers, resulting in the increased use of physicochemical fi ltration for the removal of bacteria from potable water and wastewater because of its simplicity, high effi ciency and low-costs. Th e attachment of bacteria to a fi lter surface is dictated by the adsorption mechanism, and this process does not produce by-products, such as those found in the chemical disinfection process used for water purifi cation [5]. Th e use of granular fi ltration marked the end of waterborne epidemics in the developed world more than a century ago.…”

Section: Application Of Colloidal Filtration Theory To Bacterial Attamentioning

confidence: 99%

Application of colloidal filtration theory to bacterial attachment in textile fibrous media

Roy¹,

Ghosh²,

Bhowmick³

2018

TEK

View full text Add to dashboard Cite

A mechanism to remove Pseudomonas bacteria from contaminated water using textile fi brous media was proposed in this study. The attachment of Pseudomonas bacteria to nylon fi brous media was studied in a laboratory column experiment. A systematic study was carried out to investigate the attachment of bacteria to fi brous material as a function of media mass at a constant solution chemistry. The single-collector contact effi ciency and collision effi ciency from the interaction between bacteria and fi brous media were calculated applying a semi-empirical approach of clean-bed fi ltration theory. The experimental results indicate that removal effi ciency increases with an increase in media mass up to a certain level. This is due to the change in single-collector contact effi ciency and attachment/collision effi ciency, as observed from experimental data regarding removal effi ciency.

show abstract

“…Membrane filtration, though very useful for disinfection of water, suffers from fouling which results in frequent replacement of the membranes that raises the cost of the entire treatment process. Recently, adsorption technique has been a favoured method to remove bacteria and viruses in water due to its simplicity, high efficiency, relatively cheap, easily regenerated and readily available [14] . Furthermore, adsorption process does not produce toxic disinfection by-products unlike in chemical disinfection methods.…”

Section: Introductionmentioning

confidence: 99%

Disinfection of water with new chitosan-modified hybrid clay composite adsorbent

Unuabonah

Adewuyi

Kolawole

et al. 2017

Heliyon

View full text Add to dashboard Cite

Hybrid clay composites were prepared from Kaolinite clay and Carica papaya seeds via modification with chitosan, Alum, NaOH, and ZnCl2 in different ratios, using solvothermal and surface modification techniques. Several composite adsorbents were prepared, and the most efficient of them for the removal of gram negative enteric bacteria was the hybrid clay composite that was surface-modified with chitosan, Ch-nHYCA1:5 (Chitosan: nHYCA = 1:5). This composite adsorbent had a maximum adsorption removal value of 4.07 × 106 cfu/mL for V. cholerae after 120 min, 1.95 × 106 cfu/mL for E. coli after ∼180 min and 3.25 × 106 cfu/mL for S. typhi after 270 min. The Brouers-Sotolongo model was found to better predict the maximum adsorption capacity (qmax) of Ch-nHYCA1:5 composite adsorbent for the removal of E. coli with a qmax of 103.07 mg/g (7.93 × 107 cfu/mL) and V. cholerae with a qmax of 154.18 mg/g (1.19 × 108 cfu/mL) while the Sips model best described S. typhi adsorption by Ch-nHYCA1:5 composite with an estimated qmax of 83.65 mg/g (6.43 × 107 cfu/mL). These efficiencies do far exceed the alert/action levels of ca. 500 cfu/mL in drinking water for these bacteria. The simplicity of the composite preparation process and the availability of raw materials used for its preparation underscore the potential of this low-cost chitosan-modified composite adsorbent (Ch-nHYCA1:5) for water treatment.

show abstract

Removing human immunodeficiency virus (HIV) from human blood using immobilized heparin

Cited by 20 publications

References 15 publications

Pharmacology of Heparin and Related Drugs

Pharmacology of Heparin and Related Drugs

Application of colloidal filtration theory to bacterial attachment in textile fibrous media

Disinfection of water with new chitosan-modified hybrid clay composite adsorbent

Contact Info

Product

Resources

About