Renal autotransplantation in the treatment of hypertension and uraemia due to renal artery stenosis

This paper reports the results of reconstructive renal arterial operations on 23 patients who underwent surgery because it was considered that renal artery disease was contributing to their chronic renal failure. The median pre-operative serum creatinine in this group of patients was 0.77 (range 0.15-1.14 mmol/l) and all patients had severe hypertension. In 10 cases there was evidence of other renal disease (analgesic nephropathy, 8; glomerulonephritis, 2). Operation performed was unilateral aortorenal reconstruction in 21 patients and bilateral reconstruction in 2 patients. There were four in-hospital deaths. In 15 patients operation was judged to have improved their renal function with a fall of median pre-operative creatinine from 0.34 mmol/l (0.15-0.84) to a median creatinine of 0.15 (0.05-0.52). There was one intra-operative death. There were 7 patients in whom operation led to no improvement in renal function. Their median pre-operative creatinine was 0.90 (0.32-1.14 mmol/l), and this pre-operative creatinine differs significantly from the group whose creatinine fell after surgery (P less than 0.002). Renal artery reconstruction should be considered in patients with chronic renal failure who have correctable arterial lesions.

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Reconstructive renal vascular surgery for chronic renal failure

Jamieson

Clarkson

Woodroffe

et al. 1984

Journal of British Surgery

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Renal Autotransplantation in the Treatment of Hypertensive Disease Associated with Unilateral Renal Artery Stenosis

Góes

Lucon

1981

Journal of Urology

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The Role of Autotransplantation in the Treatment of Severe Arteriorenal Hypertension: Ten Case Reports

Hadjiyannakis

1980

Vascular Surgery

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This report summarizes our experience with 10 kidney autotransplanta tions performed from November 1972 to October 1978 in 9 patients with extended stenosis of renal arteries following fibromuscular hyperplasia. One of the cases involved a 5-year-old girl with a single kidney. Five of the 9 patients had presented with obviously decreased renal function. There were no deaths. In the first patient the graft was removed after 10 months and a successful allotransplantation was performed with a mother donor, 5 years ago. In 2 of the 9 patients single kidney aortorenal bypass had been unsuccessfully performed elsewhere. All the patients now have a normal blood pressure without having to take any antihypertensive agents, 3 to 70 months after the autotransplantation.

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Renal autotransplantation in the treatment of hypertension and uraemia due to renal artery stenosis

Cited by 3 publications

References 16 publications

Reconstructive renal vascular surgery for chronic renal failure

Reconstructive renal vascular surgery for chronic renal failure

Renal Autotransplantation in the Treatment of Hypertensive Disease Associated with Unilateral Renal Artery Stenosis

The Role of Autotransplantation in the Treatment of Severe Arteriorenal Hypertension: Ten Case Reports

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