“…Patients with HIVAN typically present with nephrotic-range proteinuria, renal insufficiency, and enlarged kidneys by ultrasound, 27 but do not typically have hypertension. While it has been suggested that male gender, 20,28 use of intravenous drugs, [18][19][20][21]22,23,29 and low CD4 count 30 are all risk factors for HIVAN, conclusions from these studies are limited by selection for more aggressive disease courses that may affect external generalizability.…”