Renal Dysplasia in a Shih Tzu Dog in Japan.

Ohara, Kiminari; Kobayashi, Yoshiyasu; Tsuchiya, Naho; Furuoka, Hidefumi; Matsui, Takane

doi:10.1292/jvms.63.1127

Cited by 14 publications

(11 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A displasia renal é uma enfermidade caracterizada por distúrbios no desenvolvimento embrionário dos rins (Kerlin e Winkle, 1995;Hoppe e Karlstam, 2000;Ohara et al, 2001). Acomete animais jovens, com menos de dois anos de idade (Brum et al, 2008).…”

Section: Discussionunclassified

Displasia renal em cão da raça Rotweiller

Volkweis¹,

Almeida²,

Wong³

et al. 2012

Arq. Bras. Med. Vet. Zootec.

View full text Add to dashboard Cite

RESUMODescreveram-se os achados clínicos e patológicos de um caso de displasia renal em um cão da raça Rotweiller com oito meses de idade. O animal apresentou vômitos, emagrecimento, polidpsia e poliúria. Houve elevação sanguínea de creatinina, cálcio e da fosfatase alcalina. À necropsia, notaram-se os rins diminuídos de tamanho, com estruturas císticas proeminentes sobre a superfície natural do órgão e, ao corte, firmes e com estruturas císticas distribuídas pelo parênquima. Na avaliação histológica, havia glomérulos imaturos, fibroplasia intersticial e dilatação cística tubular. (Pereira et al., 2007;Azizi et al., 2010). É uma enfermidade frequentemente relatada em cães das raças Shih-Tzu e Lhasa

show abstract

Section: Discussionunclassified

Displasia renal em cão da raça Rotweiller

Volkweis¹,

Almeida²,

Wong³

et al. 2012

Arq. Bras. Med. Vet. Zootec.

View full text Add to dashboard Cite

show abstract

“…Renal dysplasia, rarely reported in cats (ARESU et al, 2009), is a structural disorganization resulting from abnormal differentiation and presence of abnormal structures in nephrogenesis of hereditary or acquired origin (PICUTT;LEWIS, 1987;LEES, 1996;OHARA et al, 2001;CIANCIOLO;MOHR, 2015). Usually, these abnormalities are congenital, but in felines, canines, and pigs with a nephrogenic zone active at birth, dysplasia can be caused by diseases in the neonatal period where tissue differentiation is complete (CIANCIOLO; MOHR, 2015).…”

Section: Introductionmentioning

confidence: 99%

Urethral dysontogenic metaplasia in cat with bilateral renal dysplasia

Sapin

Silva

Scheid

et al. 2017

SCA

View full text Add to dashboard Cite

This paper to describe a case of dysontogenic urethral metaplasia in a one month old mongrel feline who also had bilateral renal dysplasia. Dysontogenic metaplasia in cats are scarce and this change may be associated with renal dysplasia and/or lower urinary tract. The animal had history of abdominal enlargement since birth and dysuria, eliminating urine only dropwise. Due to the poor prognosis we opted for euthanasia. At necropsy was observed enlarged and distended bladder, reduced kidneys and dilated and tortuous ureters. The urethra was thickened, hard to cut, and histologically, was replacing the connective tissue, cartilage and endochondral ossification areas, which features dysontogenic metaplasia. Both kidneys presented primitive appearance featuring dysplasia. Dysontogenic metaplasia in urinary tract feline with renal dysplasia, has not been described. Key words: Congenital disease. Malformation. Nephropathy. ResumoEste trabalho tem como objetivo descrever um caso de metaplasia disontogênica uretral em um felino sem raça definida de um mês de idade, que também apresentava displasia renal bilateral. Dados sobre metaplasia disontogênica em felinos são escassos e a alteração pode estar associada a displasia renal e/ ou do trato urinário inferior. O animal apresentava histórico de aumento abdominal desde o nascimento e disúria, eliminando a urina apenas por gotejamento. Devido ao prognóstico desfavorável optou-se pela eutanásia. Na necropsia observou-se bexiga aumentada e dilatada, rins diminuídos e ureteres dilatados e tortuosos. A uretra apresentava-se espessada e firme ao corte, e histologicamente, havia substituição ao tecido conjuntivo, áreas de cartilagem e zonas de ossificação endocondral, o que caracteriza metaplasia disontogênica. Ambos os rins apresentavam aspecto primitivo caracterizando a displasia renal. A metaplasia disontogênica no trato urinário de felinos com displasia renal, não tem sido descrita. Palavras-chave: Doença congênita. Malformação. Nefropatia.

show abstract

“…A number of renal pathologies with a cystic component have been described in dogs including: Polycystic Kidney Disease (PKD) [25,27,[32][33][34]; juvenile nephropathy (JN) [5,26,35]; renal dysplasia [12,28,30,31,36,42]; medullary sponge kidney [2]; glomerulocystic kidney disease (GCKD) [4,38,46]; primary renal neoplasia such as hereditary multifocal renal cystadenocarcinomas and nodular dermatofibrosis (RCND) [3,19,20,29,48]; renal cystadenoma [23], and acquired cysts [37]. PKD is a genetic disorder characterized by bilateral renal cysts of varying size and number distributed uniformly in the cortex and medulla [32].…”

mentioning

confidence: 99%

“…Renal dysplasia may be defined as a disorganized development of the renal parenchyma that is caused by the defective interaction of the ureteric bud and the metanephric blastema [36]. Renal dysplasia has been reported to occur infrequently in a large number of canine breeds [1,12,14,28,30,31,42]. The disease may be either inherited or acquired and two possible clinical manifestations [1] could be observed: a benign form in animals that are clinically well but with polyuria and polydipsia, and a more aggressive form in which polyuria and polydipsia are associated at a very early stage to signs of uraemia.…”

mentioning

confidence: 99%

Juvenile Nephropathy in a Boxer Dog Resembling the Human Nephronophthisis-Medullary Cystic Kidney Disease Complex

Basile¹,

Muda²,

Giannakakis

et al. 2011

The Journal of Veterinary Medical Science

View full text Add to dashboard Cite

ABSTRACT. A juvenile nephropathy in a 4-year-old male Boxer dog, closely resembling the Nephronophthisis (NPHP)-Medullary Cystic Kidney Disease Complex (MCKD) in humans is described. Gross examination of the kidneys revealed several multiple cysts at the corticomedullary junction and in the medulla. Histological examination was characterized by a widespread tubular atrophy and dilatation, with a marked thickening of the tubular basement membrane, interstitial lymphocytic infiltration and fibrosis. Ultrastructural studies revealed dilated tubules with irregular basement membrane thickening and splitting. Lectin histochemistry investigation revealed that the cysts originated in the distal convoluted tubule and collecting duct. Having excluded all other known cystic diseases of the kidney, and based on the lectin histochemistry results, the macroscopic and histological findings of our case are highly compatible with a diagnosis of the NPHP-MCKD complex. To our knowledge, this is the first report describing this particular lesion.KEY WORDS: canine, cystic disease of the kidney, juvenile nephropathy, kidney, nephronophthisis.

show abstract

Renal Dysplasia in a Shih Tzu Dog in Japan.

Cited by 14 publications

References 4 publications

Displasia renal em cão da raça Rotweiller

Displasia renal em cão da raça Rotweiller

Urethral dysontogenic metaplasia in cat with bilateral renal dysplasia

Juvenile Nephropathy in a Boxer Dog Resembling the Human Nephronophthisis-Medullary Cystic Kidney Disease Complex

Contact Info

Product

Resources

About