Renal Function Change in Renal Calculus Disease Undergoing Urological Intervention

Abstract

Background: Urolithiasis, the third most common urological disease is one of the oldest disease known to mankind affecting both males and female in a proportion of approximately 2:1. 1 It is very frequently seen disease in recent times, with an increasing incidence and prevalence, with a significant economic impact associated with its treatment. Although there are numerous reports about the end results, its effects on renal functions are not well studied quantitatively. Renal dysfunction due to an obstructing renal or urinary tract calculus improves or resolves upon the timely removal by the appropriate method. However, stone-removing procedures may have a negative impact on renal function through direct or indirect mechanisms. 5 Aims and Objectives: To study the renal function changes in patients of renal calculus disease who will undergo Urological Intervention(s), assess the factors that influence the post procedural renal function change (s) following the urological intervention and evaluate the Outcomes of Percutaneous Nephrolithotomy compared to Shock Wave Lithotripsy on renal function changes. Materials and Methods: This is Hospital based descriptive study conducted in Department of Medicine and Urology, RIMS, Imphal during September 2016 to August 2018 amongst patient admitted in the Medicine/ Urology department in the age group of 18 years or more, with renal stone disease for Urological interventions during the study period Results: It was concluded that renal function does not change post urological intervention & that patients presenting with kidney stone disease & renal insufficiency experience higher likelihood of renal function deterioration after treatment of calculous disease. It was also observed comorbidities like hypertension, diabetes or anaemia were not significant predictors or determinants of postoperative renal function deterioration. There was also improvement of hydronephrosis post intervention.