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BACKGROUNDBP and heart rate fluctuate over a 24 hours period. External stresses and subject's activities have direct effects on BP and heart rate. BP and heart rate also vary according to their own circadian rhythm. 1 Stress can cause hypertension through repeated elevations of BP. METHODSThis is a cross-sectional study conducted in Regional Institute of Medical Sciences (RIMS) Hospital amongst Health Workers. RESULTSMost of the Health Workers are Males (63%) and in the age group of 21-30 years with mean age of 30.22±6.32. Both systolic and diastolic hypertension was found during day, night and over 24 hours duty. Systolic hypertension during day duty was 10% which increases to 39% during night time duty. Systolic and diastolic hypertension during the 24 hours duty was found to be 22% and 39% respectively. DBP hypertension during day time duty was found to be 26% which increases to 48% during night time duty. The overall hypertensive distribution of hypertension of health workers is 29%, 52% and 42% during day time, night time and 24 hours duty respectively. CONCLUSIONSDuring Night time duty, more Health Workers were hypertensive (52%) as compared to day time duty which was lesser (29%) and over the 24 hours duty 42% of health workers were hypertensive. Thus, the present findings suggest effects of occupational stress on ABP measured at work, in night shift and over 24 hours period among health workers. In the long run, stressful night duty increases the risk of development of hypertension. HOW TO CITE THIS ARTICLE:Singh TB, Kikon EC, Deba TS, et al. Ambulatory blood pressure monitoring in health workers during night shift duty.

Background: Antiretroviral therapy (ART) have changed the outlook of people living with HIV (PLHIV) by transforming the dreaded infection to a chronically manageable disease. However, there is scant of reports which analyses quantitatively the survival benefit of PLHIV under ART. Objectives of this study were to determine the survival time of adult PLHIV who are on ARV. To analyse the factors determining survival outcome of PLHIV on ARV.Methods: This was an observational study in centre of excellence (COE) ART Centre, RIMS, Imphal from April 2004 to December 2009. Details from the data entered in documents of the ART programme were followed up every 3 months for 60 months from the date of initiation of ARV. All PLHIV above 18 years of age and undergoing antiretroviral therapy were included.Results: Survival rate following initiation of ARV was found to be significantly high among PLHIV. Higher CD4 count at the time of ARV initiation had better prognosis. Mortality was high among IDUs and they had high incidence of co-infections with HCV and HBV. The currently available ARV drugs under NACO programme have better suppression of HIV, are less toxic, low pill burden. The combined regimen used in the earlier days were not much inferior to the current ARV drugs if initiated timely with proper prophylaxis of OIs, good adherence, good nutrition and timely management of toxicities and IRIS.Conclusions: Timely treatment with ARV drugs provided under the national programme with good adherence and regular follow-up improves the survival of PLHIV.

Background: Urolithiasis, the third most common urological disease is one of the oldest disease known to mankind affecting both males and female in a proportion of approximately 2:1. 1 It is very frequently seen disease in recent times, with an increasing incidence and prevalence, with a significant economic impact associated with its treatment. Although there are numerous reports about the end results, its effects on renal functions are not well studied quantitatively. Renal dysfunction due to an obstructing renal or urinary tract calculus improves or resolves upon the timely removal by the appropriate method. However, stone-removing procedures may have a negative impact on renal function through direct or indirect mechanisms. 5 Aims and Objectives: To study the renal function changes in patients of renal calculus disease who will undergo Urological Intervention(s), assess the factors that influence the post procedural renal function change (s) following the urological intervention and evaluate the Outcomes of Percutaneous Nephrolithotomy compared to Shock Wave Lithotripsy on renal function changes. Materials and Methods: This is Hospital based descriptive study conducted in Department of Medicine and Urology, RIMS, Imphal during September 2016 to August 2018 amongst patient admitted in the Medicine/ Urology department in the age group of 18 years or more, with renal stone disease for Urological interventions during the study period Results: It was concluded that renal function does not change post urological intervention & that patients presenting with kidney stone disease & renal insufficiency experience higher likelihood of renal function deterioration after treatment of calculous disease. It was also observed comorbidities like hypertension, diabetes or anaemia were not significant predictors or determinants of postoperative renal function deterioration. There was also improvement of hydronephrosis post intervention.