Renal mucinous and tubular spindle cell carcinoma: a clinicopathological study of 4 cases

Mucinous tubular and spindle cell carcinoma of the kidney

“…MTSCCs are polymorphic neoplasms showing a wide range of morphologic variability [2]. Histologically, they are generally characterized by the presence of cuboidal and spindle cells [9].…”

“…Some cases might show predominance of various components: some MTSCCs may show spindle cell predominance and mimic sarcomatoid carcinomas, and others may show tubular cell predominance and mimic the solid variant of papillary RCC [2]. Other characteristic features include tumors with poor mucin content, areas with extracellular hyaline matrix and blue-tinged mucin within tubules, and solid areas with epithelioid cells [2]. MTSCCs are known to originate from the collecting duct epithelium or cells of the loop of Henle [8].…”

“…It is a relatively lowgrade carcinoma and is associated with a good prognosis [2]. The clinical characteristics of MTSCC are similar to those of papillary renal cell carcinoma (RCC) with sarcomatoid transformation.…”

A case of renal mucinous tubular and spindle cell carcinoma

“…Gaafar et al. reported that MTSCC‐K accounts for less than 0.8% of renal neoplasms 2 . In fact, even though this pathological entity was first recognized in 2001 by Parwani et al.…”

“…Mucinous tubular and spindle cell carcinoma of the kidney (MTSCC‐K) is a relatively rare pathological entity that has recently been described in the World Health Organization 2004 renal cell carcinoma (RCC) classification 1 . Previously, it was reported that this type of RCC showed relatively good prognosis 2 . A precise differential diagnosis between MTSCC‐K and papillary RCC with sarcomatoid transformation is important for predicting patient prognosis 3 .…”