Acute renal replacement therapy (RRT) is a mainstay therapy, 1 that is applied in 8%-13.5% of critically ill patients with severe acute kidney injury (AKI). [2][3][4][5] Noticeably, a previous survey showed that intermittent hemodialysis (IHD), peritoneal dialysis (PD), and continuous RRT (CRRT) were widely applied for the modalities of acute RRT. 6 Over the past decade, CRRT has become the preferred modality among nephrologists and intensivist community. 7 Data from AKI-EPI study clearly found that CRRT is the predominant form of initial acute therapy in over 75% of critically ill patients 3 and had become widely accepted worldwide. However, little is known about CRRT adoption and practice in the developing world. Many national and international surveys of the current practice of RRT management were previously conducted in developed countries such as Australia, Europe, 7 New Zealand, 8 UK, 9 and Japan. 10 In this review, we focus on the current situation of CRRT practice in the developing world, barriers to implement the CRRT program, and strategies to improve the adoption of CRRT in the developing world.
| CURRENT S ITUATI ON OF CRRT IN THE DE VELOPING WORLDThe epidemiology of AKI and acute RRT in resource-limited settings have not been well-established due to their limited healthcare resources, lack of adequate patient registry, and low awareness of AKI.Recently, there were published meta-analyses of global AKI burden reporting that KDIGO-defined pooled AKI incidences in hospitalized