Renal Transplantation in Children and Adolescents

Fennell, Robert S.; Garin, Eduardo H.; Pfaff, William; Brient, Bruce W.; Iravani, Abdollah; Walker, R. Dixon; Richard, George A.

doi:10.1177/000992287901800901

Cited by 8 publications

(3 citation statements)

References 11 publications

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“…The chronological age [3,4,6,18] and the sex [4,6,11] of the pediatric allograft recipient have been shown to influence growth following transplantation. In general, females and patients transplanted after their 12th birthday have not grown well.…”

Section: Discussionmentioning

confidence: 99%

“…Allograft function was monitored for each patient by blood urea nitrogen (BUN), serum creatinine and creatinine clearances obtained during clinic visits [6]. Blood pressure was measured with the patient in the sitting position and converted to the percentile rank for age and sex [27].…”

Section: Recordsmentioning

confidence: 99%

“…Average daily prednisone dosage, total number of boluses of methylprednisolone sodium succinate, alternate versus daily administration of prednisone, and percentile rank for blood pressure were computed for each 6-month interval. The prednisone tapering schedule and indications for the use of methylprednisolone have been described elsewhere [6].…”

Section: Recordsmentioning

confidence: 99%

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Statistical analysis of statural growth following kidney transplantation

et al. 1986

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Factors affecting the growth rates of 59 children and adolescents for the first 2 years following kidney transplantation were evaluated. The factors assessed were age at transplantation, renal function, prednisone dosage, donor source, and prior history of transplantation. The observed growth velocity was expressed as the percentage of the growth velocity predicted by bone age. Normal growth (greater than or equal to 80%) was exhibited by 37% of the patients and 22% had accelerated growth (greater than or equal to 100%). The chronological age at transplantation did not correlate significantly with growth when bone age was used as the reference for expected velocity. Males grew better than did females. There was a unique sex/race interaction with black males growing most rapidly. Better renal function, the ability to lower prednisone dosage, alternate day prednisone, and a decreasing diastolic blood pressure were positively correlated with better growth rates after transplantation. Donor source and prior history of transplantation did not significantly influence growth rate.

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