1945
DOI: 10.1136/adc.20.103.129
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Renal venous thrombosis and infarction in the newborn

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1951
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Cited by 34 publications
(3 citation statements)
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“…In the classic description of spontaneous nRVT, the thrombus first forms in the small vessels of the kidney and later extends into the renal vein. This had been identified in autopsy studies that identified reactive changes in cells nearby thrombi in small intrarenal veins that were absent near larger veins, suggesting that the renal vein becomes involved secondary to resultant stasis (20). Kidneys are vulnerable to thrombosis due to slow perfusion through the double capillary network, especially in the context of hemoconcentration or hypercoagulability.…”
Section: Discussionmentioning
confidence: 96%
“…In the classic description of spontaneous nRVT, the thrombus first forms in the small vessels of the kidney and later extends into the renal vein. This had been identified in autopsy studies that identified reactive changes in cells nearby thrombi in small intrarenal veins that were absent near larger veins, suggesting that the renal vein becomes involved secondary to resultant stasis (20). Kidneys are vulnerable to thrombosis due to slow perfusion through the double capillary network, especially in the context of hemoconcentration or hypercoagulability.…”
Section: Discussionmentioning
confidence: 96%
“…It is conceivable th a t th e y are the resu lt of sm all p a ra doxical em bolic phen o m en a issu in g from the renal venous th ro m b o sis. T h e asso ciatio n o f d ia rrh e a , v o m itin g an d d e h y d ra tio n w ith renal venous th ro m b o sis has b een com m on a n d it h as a p p a re n tly play ed a role in th e d ev elo p m en t o f th is condition, in th e m a jo rity of the re p o rte d cases (1,10,16,19,20). B irth tra u m a as its cause has been m en tio n ed (5, 18, 21) b u t it did n o t a p p a re n tly p lay an im p o rta n t role in th e occu rren ce o f th e ren al vein th ro m b o sis o f this series.…”
Section: Discussionmentioning
confidence: 99%
“…In the fetus and newborn, focal and diffuse infarctional damage may occur not only in the brain, but also in the kidneys, adrenals, and other structures (Csermely, 1972;Morison, 1945;Ylppo, 1919). The brain, however, proves to be the most vulnerable organ, the most common target, and in this respect, with most serious consequences.…”
Section: Factors Determining Location Of Cerebral Lesionsmentioning
confidence: 99%