Renin and ovarian vascularization in cows with follicular cysts after epidural administration of a GnRH analogue

Rizzo, Annalisa; Minoia, Giuseppe; Trisolini, Carmelinda; Mutinati, Maddalena; Spedicato, Massimo; Manca, R.; Sciorsci, Raffaele Luigi

doi:10.1016/j.anireprosci.2009.02.016

Cited by 13 publications

(12 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The invoking effects on the vessels are thereby first of all adapted from the Angiotensin II-AT1R-pathway (41–44). To be contrary to this, the restitution of the luteal vasculature is mediated by the AT2R-pathway (45).…”

Section: Physiological Role Of the Ras In The Reproductive Tractmentioning

confidence: 99%

Local Renin-Angiotensin System in the Reproductive System

Herr

Bekes²,

Wulff³

2013

Front. Endocrinol.

View full text Add to dashboard Cite

The renin-angiotensin system (RAS) is well known as regulator of electrolytes and blood pressure. Besides this function, there are numerous studies supporting the idea of a local tissue RAS. This system controls the local activity of the different RAS family members, especially of the functional proteins Angiotensin II and Angiotensin (1–7). Those antagonistically acting proteins have been described to be expressed in different organ systems including the human reproductive tract. Therefore, this local RAS has been suspected to be involved in the control and regulation of physiological and pathological conditions in the female reproduction tract. This review of the available literature summarizes the physiological influence of the RAS on the follicular development, ovarian angiogenesis, and placental- and uterine function. In addition, in the second part the role of the RAS concerning ovarian- and endometrial cancer becomes elucidated. This section includes possible novel therapeutic strategies via inhibition of RAS-mediated tumor growth and angiogenesis. Looking at a very complex system of agonistic and antagonistic tissue factors, it may be supposed that the RAS in the female reproduction tract will be of rising scientific interest in the upcoming years.

show abstract

Section: Physiological Role Of the Ras In The Reproductive Tractmentioning

confidence: 99%

Local Renin-Angiotensin System in the Reproductive System

Herr

Bekes²,

Wulff³

2013

Front. Endocrinol.

View full text Add to dashboard Cite

show abstract

“…The efficacy of Lecirelin has been previously proved during clinical studies (Baruselli et al, 2001;Robbe et al, 2002;Martin et al, 2006;Carluccio et al, 2007;Fries et al, 2010;) and it has also been demonstrated that epidural route is more efficient than the intramuscular one (Rizzo et al, 2009).…”

Section: Discussionmentioning

confidence: 89%

“…Administered at the time of insemination, Lecirelin improves the reproductive performance of dairy cattle (Martin et al, 2006) and positive results have been obtained also in follicular cysts affected cows (Robbe et al, 2002;Rizzo et al, 2009Rizzo et al, , 2011.…”

Section: Introductionmentioning

confidence: 94%

Epidural administration of Lecirelin for inducing ovulation in female dromedary camels ( Camelus dromedarius ): A preliminary study

Monaco

El-Bahrawy

Lacalandra

2017

Small Ruminant Research

View full text Add to dashboard Cite

“…It has further been demonstrated that gonadotropins may increase local RAS(Pereira et al, 2009;Kasum, 2010) in different species. Consistently, Rizzo et al demonstrated a significant decrease in ovarian cyst vascularization(Rizzo et al, 2009) after GNRH analogue treatment of cows, which was associated with elevated serum renin levels. These authors suggested from their data that in GNRH-sedated ovaries the activity of the local RAS is reduced which may be associated with reduced ovarian blood flow.…”

mentioning

confidence: 87%

Is there a role of the local tissue RAS in the regulation of physiologic and pathophysiologic conditions in the reproductive tract?

Schwentner

Wöckel

Herr

et al. 2011

J Renin Angiotensin Aldosterone Syst

View full text Add to dashboard Cite

The renin-angiotensin system is well known as a systemic endocrine pathway that regulates blood pressure and salt-water metabolism. In addition to the systemic renin-angiotensin system there is evidence in different species for the presence of a local tissue renin-angiotensin system, which allows local production of the bioactive peptides angiotensin II and angiotensin (1-7). The local renin-angiotensin system has been found in a variety of tissues including tissue of the human reproductive tract. Thus, it was suspected that it may have important functions in the local hormonal microenvironment. Here, a systematic literature search was undertaken to review whether there is evidence for regulatory functions of the local tissue renin-angiotensin system in the human reproductive tract under physiological and pathological conditions.

show abstract

Renin and ovarian vascularization in cows with follicular cysts after epidural administration of a GnRH analogue

Cited by 13 publications

References 16 publications

Local Renin-Angiotensin System in the Reproductive System

Local Renin-Angiotensin System in the Reproductive System

Epidural administration of Lecirelin for inducing ovulation in female dromedary camels ( Camelus dromedarius ): A preliminary study

Is there a role of the local tissue RAS in the regulation of physiologic and pathophysiologic conditions in the reproductive tract?

Contact Info

Product

Resources

About