2007
DOI: 10.1111/j.1530-0277.2007.00476.x
|View full text |Cite
|
Sign up to set email alerts
|

Repeated Light–Dark Phase Shifts Modulate Voluntary Ethanol Intake in Male and Female High Alcohol‐Drinking (HAD1) Rats

Abstract: Background: Chronic disruption of sleep and other circadian biological rhythms, such as occurs in shift work or in frequent transmeridian travel, appears to represent a significant source of allostatic load, leading to the emergence of stress-related physical and psychological illness. Recent animal experiments have shown that these negative health effects may be effectively modeled by exposure to repeated phase shifts of the daily light-dark (LD) cycle. As chronobiological disturbances are thought to promote … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

2
30
1

Year Published

2009
2009
2024
2024

Publication Types

Select...
6
2

Relationship

0
8

Authors

Journals

citations
Cited by 43 publications
(35 citation statements)
references
References 69 publications
(105 reference statements)
2
30
1
Order By: Relevance
“…Chronic circadian desynchrony that was induced by repeated light/dark phase shifts resulted in the sex-specific modulation of voluntary ethanol intake in High-Alcohol-Drinking-1 rats, reducing ethanol intake in males while slightly increasing intake in females (Clark et al, 2007). In summary, there are few studies that have compared ethanol relapse models in male and female rodents, but there is the suggestion of an enhanced ADE and enhanced response to a stressor in females.…”
Section: Sex Differences In the Preoccupationmentioning
confidence: 99%
“…Chronic circadian desynchrony that was induced by repeated light/dark phase shifts resulted in the sex-specific modulation of voluntary ethanol intake in High-Alcohol-Drinking-1 rats, reducing ethanol intake in males while slightly increasing intake in females (Clark et al, 2007). In summary, there are few studies that have compared ethanol relapse models in male and female rodents, but there is the suggestion of an enhanced ADE and enhanced response to a stressor in females.…”
Section: Sex Differences In the Preoccupationmentioning
confidence: 99%
“…One important feature of AAA models is the definition of biologically meaningful levels of alcohol, either in vitro or in vivo, and their relationship to blood alcohol levels (BAL) in humans. This is an important requirement of the research models of AAA, because BAL can be detected as soon as minimal amounts of alcohol are ingested [85] , however measurable affects of alcohol on physiology and/or behavior is established at 0.08% or above this level, with individual variations depending on the species, metabolic particularities, age, gender and genetic background [86][87][88][89][90][91][92][93][94][95][96][97] . It is also important to identify that AAA models differ by their route of alcohol delivery to achieve alcohol intoxication, some of them being physiological, such as oral administration, while others being non-physiological, when ethanol is administered by parenteral routes.…”
Section: Models Of Aaamentioning
confidence: 99%
“…Among non-human vertebrates commonly involved in alcohol research are primates [90,91,148] , pigs [104,120] , dogs [114,121] , mice [70,72,74,86,89,96,109,118,119,141] , rats [88,94,108,149,150] and rabbits [132] . The rodent AAA models (mice and rats) are used most frequently due to their relatively well-defined genetic background and the availability of diverse genetic traits, including those coding for high or low alcohol consumption [88,89,96,109] .…”
Section: Non-human Aaa Modelsmentioning
confidence: 99%
See 1 more Smart Citation
“…For example, rats and mice express pronounced daily rhythms in voluntary alcohol intake and time-dependent responses to ethanol [22,38,39,40]. Chronic ethanol administration influences various circadian rhythms (e.g.…”
Section: Discussionmentioning
confidence: 99%