Repelentes de insetos: recomendações para uso em crianças

Stefani, Germana Pimentel; Pastorino, Antônio Carlos; Castro, Ana Paula Beltran Moschione; Fomin, Ângela B. F.; Jacob, Cristina Miuki Abe

doi:10.1590/s0103-05822009000100013

Cited by 26 publications

(27 citation statements)

References 34 publications

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“…The main way of combating the spreading of these diseases is the control of the vectors population and also reducing the contact between humans and mosquitoes. Considering that prophylactic measures like vaccines are still not available for most of these diseases, the use of repellents is fundamental …”

Section: Introductionmentioning

confidence: 99%

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Encapsulation ofN,N‐diethyl‐meta‐toluamide (DEET) via miniemulsion polymerization for temperature controlled release

Gomes

Bigon

Montoro

et al. 2018

J of Applied Polymer Sci

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N,N-diethyl-meta-toluamide (DEET), an insect repellent, can be successfully encapsulated in poly(n-butyl methacrylate-comethyl methacrylate) nanospheres via direct miniemulsion polymerization. Stable and low polydisperse nanospheres with a number average diameter of 114 AE 37 nm were obtained. It is shown that DEET is an effective costabilizer and that sodium lauryl sulfate is a suitable surfactant. The nanospheres glass-transition temperature (T g ) can be tuned by adjusting the ratio between n-butyl methacrylate and methyl methacrylate in the monomer formulation. The repellent reduced the polymerization reaction rate and the copolymer molecular weight, and changed the nanoparticle morphology. The release rate of the encapsulated DEET provides repellency for over 9 h and is and more controlled when compared to the free DEET. Results show the mechanism of release is temperature dependent. At temperatures close to and lower than the polymer T g , polymer relaxation is the limiting mechanism. At higher temperatures, Fickian diffusion limits the overall release. Thus, the DEET release rate can be tuned by adjusting the copolymer T g . This ensures this material a great potential as temperature-dependent delivery system. An alternative of protection for this vulnerable population is the encapsulation and further application of DEET in fabrics, for instance. Thus, not only the DEET would not be applied directly to the skin, but its evaporation could be slowed down, increasing the repellency time of this substance.The encapsulation of substances can be achieved with a large number of techniques, like coacervation, 8 solvent evaporation, 9 and polymerization techniques 10,11 and there is also a considerable variety of carrier systems, such as liposomes, polymeric nanocapsules, micelles, etc. [12][13][14] One advantage of using polymeric systems for encapsulation is the possibility of tailoring the polymer chain, which makes them suitable for a wide range of applications, like drug delivery, 15,16 controlled release of fragrances, 17-19 and cells encapsulation. 20,21 The miniemulsion polymerization is a simple technique which allows the formation of polymer particles with controlled Additional Supporting Information may be found in the online version of this article.

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Section: Introductionmentioning

confidence: 99%

“…Some examples of substances that are topically applied are essential oils (citronella oil, for instance), icaridin, and N,N ‐diethyl‐ meta ‐toluamide (DEET), the latter being one of the most effectives, mainly because essential oils are very volatile …”

Section: Introductionmentioning

confidence: 99%

Encapsulation ofN,N‐diethyl‐meta‐toluamide (DEET) via miniemulsion polymerization for temperature controlled release

Gomes

Bigon

Montoro

et al. 2018

J of Applied Polymer Sci

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“…Its adoption as a prevention strategy promoted reduction in malaria-associated mortality in China and Africa, as well as cutaneous leishmaniasis infection in South America and the Middle East [2][3][4] . However, children are restricted to certain products or concentrations, according to age, making them susceptible to illness 5 . N,N-Diethyl-3-methylbenzamide (DEET) at a concentration of 30-50% is the best known repellent substance; however, its administration is limited by toxicity and skin irritation, contraindicating it in children younger than 10 years.…”

Section: Dear Editormentioning

confidence: 99%

“…Icaridin at a concentration of 20-25% is a compound derived from piperidine, found in black pepper (Piper nigrum). It is highly effective, with a low rate of sensitization and is safe to use in children older than 2 years of age; however, studies have not been conducted in pregnant women [5][6][7] .…”

Section: Dear Editormentioning

confidence: 99%

Efficacy of the main repellents available in the Brazilian market against Aedes aegypti bites under concentrations applied to pediatric populations

Silva

Olivatti

Kanda

et al. 2018

Rev. Soc. Bras. Med. Trop.

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“…Algumas medidas incluem evitar a exposição ao ar livre durante o tempo de alimentação do mosquito. 65 Em países onde a esquistossomose (uma infecção parasitária transmitida pela água) é comum, deve-se evitar crianças nadarem em água doce. Sabe-se que os casos de malária importados para os países industrializados excedem aproximadamente 25.000 anualmente.…”

Section: Picadas De Insetosunclassified

Traveling with children: beyond car seat safety

Polli

2015

Jornal de Pediatria (Versão em Português)

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Objective: To spread knowledge and instigate the health professional to give advice on childcare during travels and on child transport safety. Sources of data: Literature review through the LILACS and MEDLINE ® databases, using the terms: travel, safety, protective equipment, child, preventive medicine, retrieving articles published in the last 21 years. Summary of the findings: The authors analyzed 93 articles, of which 66 met the inclusion criteria after summaries were read. For drafting this article, the following sub-themes were proposed: getting ready to travel with children; knowing some of the transfer risks (air, land and water transportation) and exploring the destination with children (sun exposure, accommodations, altitude, food, traveler's diarrhea, insect bites) and return from the trip with children. Conclusions: Over the years, there has been an increase in the number of children who travel around the world. However, this population is still subject to health problems while traveling and may be even more susceptible than the adult age group. These problems arise from a variety of factors, including exposure to infectious organisms, the use of certain types of transportation, and participation in some activities, such as hiking at high altitudes, among others. However, when traveling with children, these risk factors can be overlooked; a trip that is considered safe for an adult might not be a good choice for this age group. The pediatric consultation should be a good opportunity to optimize preventive guidelines at the pre-trip planning. Viagem com crianças: segurança ''além da cadeirinha'' ResumoObjetivo: Proporcionar conhecimento e instigar o profissional de saúde a fornecer uma orientação aprimorada quanto aos cuidados com crianças em viagens, além de orientar o seu transporte seguro. DOI se refere ao artigo: http://dx.doi.org/10.1016/j.jped.2015.05.002 ଝ Como citar este artigo: Polli JB, Polli I. Traveling with children: beyond car seat safety. J Pediatr (Rio J). 2015;91:515---22.

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Repelentes de insetos: recomendações para uso em crianças

Cited by 26 publications

References 34 publications

Encapsulation ofN,N‐diethyl‐meta‐toluamide (DEET) via miniemulsion polymerization for temperature controlled release

Encapsulation ofN,N‐diethyl‐meta‐toluamide (DEET) via miniemulsion polymerization for temperature controlled release

Efficacy of the main repellents available in the Brazilian market against Aedes aegypti bites under concentrations applied to pediatric populations

Traveling with children: beyond car seat safety

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