Réplica

Carpio-Orantes, Luis Del; Moguel, Karla Gabriela Peniche; Díaz, Jesús Salvador Sánchez; Ramírez, Maria del Rosario Pola; Miranda, María del Pilar Mata; Méndez, Sergio García; Arroyo, Miguel Arnulfo Perfecto; Sánchez, Ishar Solís

doi:10.33588/rn.6711.2018380

“…We reviewed 135 full-text articles, of which 31 were eligible for inclusion (Fig 1). Of the 31 studies, 28 reported country-specific GBS rates from 13 LAC countries (Tables 1 & 2), 3 regional rates,[18, 35, 36] 15 background rates [18, 35–48], 11 rates during an arboviral outbreak [49–59], and 5 compared rates before and during an outbreak [27, 60–63]. Many studies presented data from Brazil (29%) and Colombia (16%), and the majority (68%) were published in 2015 or later.…”

Section: Resultsmentioning

confidence: 99%

“…In Veracruz, Mexico, del Carpio Orantes reported a GBS IR of 0.62 per 100,000 during the ZIKV epidemic in 2016 [49].…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Incidence of Guillain-Barré Syndrome (GBS) in Latin America and the Caribbean before and during the 2015–2016 Zika virus epidemic: A systematic review and meta-analysis

Capasso

¹

,

Ompad

²

,

Vieira

³

et al. 2019

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Background A severe neurological disorder, Guillain-Barré syndrome (GBS) is the leading cause of acute flaccid paralysis. Enhanced surveillance of GBS in Latin America and the Caribbean (LAC) following the 2015–2016 Zika virus (ZIKV) epidemic presents an opportunity to estimate, for the first time, the regional incidence of GBS. Methods and findings For this systematic review and meta-analysis, we searched nine scientific databases and grey literature from January 1, 1980 to October 1, 2018. Sources with primary data on incident GBS cases in LAC within a well-defined population and timeframe, published in English, Spanish, Portuguese, or French, were included. We calculated the annual GBS incidence rates (IRs) and 95% confidence intervals (CIs) for each source based on published data. Following an assessment of heterogeneity, we used random-effects meta-analysis to calculate the pooled annual IR of GBS. The study is registered with PROSPERO, number CRD42018086659. Of the 6568 initial citation hits, 31 were eligible for inclusion. Background annual GBS IRs in Latin America ranged from 0.40 in Brazil to 2.12/100,000 in Chile. The pooled annual IR in the Caribbean was 1.64 (95% CI 1.29–2.12, I 2 <0.01, p = 0.44). During the ZIKV epidemic, GBS IRs ranged from 0.62 in Mexico to 9.35/100,000 in Martinique. GBS increased 2.6 (95% CI 2.3–2.9) times during ZIKV and 1.9 (95% CI 1.1–3.4) times during chikungunya outbreaks over background rates. A limitation of this review is that the studies included employed different methodologies to find and ascertain cases of GBS, which could contribute to IR heterogeneity. In addition, it is important to consider that data on GBS are lacking for many countries in the region. Conclusions Background IRs of GBS appear to peak during arboviral disease outbreaks. The current review contributes to an understanding of the epidemiology of GBS in the LAC region, which can inform healthcare system planning and preparedness, particularly during arboviral epidemics. Trial registration Registered with PROSPERO: CRD42018086659 .

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“…We reviewed 135 full-text articles, of which 31 were eligible for inclusion ( Fig 1). Of the 31 studies, 28 reported countryspecific GBS rates from 13 LAC countries (Tables 1 & 2), 3 regional rates, [18,35,36] 15 background rates [18,[35][36][37][38][39][40][41][42][43][44][45][46][47][48], 11 rates during an arboviral outbreak [49][50][51][52][53][54][55][56][57][58][59], and 5 compared rates before and during an outbreak [27,[60][61][62][63]. Many studies presented data from Brazil (29%) and Colombia (16%), and the majority (68%) were published in 2015 or later.…”

Section: Resultsmentioning

confidence: 99%

“…On the island of Curaçao, authors found a positive temporal association between C. jejuni infections and GBS in pre-ZIKV years (1987)(1988)(1989)(1990)(1991)(1992)(1993)(1994)(1995)(1996)(1997)(1998)(1999) [47]. In Veracruz, Mexico, 75% of GBS patients tested positive for C. jejuni infection in 2017 (after the peak of ZIKV) [49]. Studies in Aruba, Brazil, and Colombia-all except the one from Aruba were conducted during the ZIKV epidemic-found no association between C. jejuni infection and GBS [43,46,50,52,55,58].…”

Section: Discussionmentioning

confidence: 97%

Incidence of Guillain-Barré Syndrome (GBS) in Latin America and the Caribbean Before and During the 2015-2016 Zika Virus Epidemic: A Systematic Review and Meta-Analysis

Capasso

¹

,

Ompad

²

,

Vieira

³

et al. 2019

View full text Add to dashboard Cite

BackgroundA severe neurological disorder, Guillain-Barré syndrome (GBS) is the leading cause of acute flaccid paralysis. Enhanced surveillance of GBS in Latin America and the Caribbean (LAC) following the 2015-2016 Zika virus (ZIKV) epidemic presents an opportunity to estimate, for the first time, the regional incidence of GBS. Methods and findingsFor this systematic review and meta-analysis, we searched nine scientific databases and grey literature from January 1, 1980 to October 1, 2018. Sources with primary data on incident GBS cases in LAC within a well-defined population and timeframe, published in English, Spanish, Portuguese, or French, were included. We calculated the annual GBS incidence rates (IRs) and 95% confidence intervals (CIs) for each source based on published data. Following an assessment of heterogeneity, we used random-effects meta-analysis to calculate the pooled annual IR of GBS. The study is registered with PROSPERO, number CRD42018086659. Of the 6568 initial citation hits, 31 were eligible for inclusion. Background annual GBS IRs in Latin America ranged from 0.40 in Brazil to 2.12/100,000 in Chile. The pooled annual IR in the Caribbean was 1.64 (95% CI 1.29-2.12, I 2 <0.01, p = 0.44). During the ZIKV epidemic, GBS IRs ranged from 0.62 in Mexico to 9.35/100,000 in Martinique. GBS increased 2.6 (95% CI 2.3-2.9) times during ZIKV and 1.9 (95% CI 1.1-3.4) times during chikungunya outbreaks over background rates. ConclusionsBackground IRs of GBS appear to peak during arboviral disease outbreaks. The current review contributes to an understanding of the epidemiology of GBS in the LAC region, which can inform healthcare system planning and preparedness, particularly during arboviral epidemics. Trial registrationRegistered with PROSPERO: CRD42018086659. Author summaryA severe neurological disorder, Guillain-Barré syndrome (GBS) is the leading cause of acute flaccid paralysis. This is the first systematic review on GBS incidence in Latin America and the Caribbean before and during arboviral disease outbreaks. There is a large subregional and annual fluctuation in the incidence of GBS. Background annual GBS incidence rates (IRs) in Latin America ranged from 0.40 in Brazil to 2.12/100,000 in Chile. The pooled annual IR in the Caribbean was 1.64 (95% CI 1.29-2.12, I 2 <0.01, p = 0.44). During the ZIKV epidemic, GBS IRs ranged from 0.62 in Mexico to 9.35/100,000 in Martinique. GBS increased 2.6 times during ZIKV and 1.9 times during chikungunya outbreaks over background rates. GBS is a costly disease, which can result in long-term disability and high mortality rates in resource constrained healthcare settings. Because GBS can be triggered by arboviral infections, baseline incidence of GBS is critical for detecting neglected tropical disease outbreaks. The current review contributes to an understanding of the epidemiology of GBS in the LAC region, which can inform healthcare system planning and preparedness.Incidence of Guillain-Barré Syndrome in LAC and arboviral disease outbreaks PLOS Neglected Tropic...

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Síndrome de Miller Fisher: Reporte de Caso y Revisión de Literatura

Granados¹,

Ortiz²,

Rincón³

2020

rev cuarzo

0

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RESUMEN: Introducción: El síndrome de Miller-Fisher (SMF) es la variante atípica más común del síndrome de Guillain-Barré (SGB) quien hace parte del grupo de enfermedades desmielinizantes agudas autoinmunes. A continuación se describe el caso de un paciente masculino de 60 años de edad que ingresa por presentar parestesias en miembros superiores de predominio distal secundario a un cuadro respiratorio alto. Al examen físico se evidencia paresia de las 4 extremidades asociado a ataxia, arreflexia,oftalmoplejía, se realiza punción lumbar evidenciándose disociación albumino-citológica y dada la rápida progresión del cuadro (deterioro en menos de 24 horas) se diagnostica SGB variante SMF con alto riesgo de insuficiencia ventilatoria por lo cual se traslada a Unidad de cuidado intensivo (UCI) donde requirió ventilación mecánica y recibió tratamiento con inmunoglobulina G humana presentando evolución clínica estacionaria tras 25 días de hospitalización, razón por la cual se remite a unidad de cuidado crónico.

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Réplica

Cited by 3 publications

References 0 publications

Incidence of Guillain-Barré Syndrome (GBS) in Latin America and the Caribbean before and during the 2015–2016 Zika virus epidemic: A systematic review and meta-analysis

Incidence of Guillain-Barré Syndrome (GBS) in Latin America and the Caribbean before and during the 2015–2016 Zika virus epidemic: A systematic review and meta-analysis

Incidence of Guillain-Barré Syndrome (GBS) in Latin America and the Caribbean Before and During the 2015-2016 Zika Virus Epidemic: A Systematic Review and Meta-Analysis

Síndrome de Miller Fisher: Reporte de Caso y Revisión de Literatura

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