Reply [to “Comment on ‘Migration of radionuclides from a granite repository’ by T. M. Krishnamoorthy et al.”]

Krishnamoorthy, T.M.; Nair, R. N.; Sarma, T.P.

doi:10.1029/93wr00577

Cited by 5 publications

(13 citation statements)

References 6 publications

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“…Resolvin D1 has been demonstrated to activate GPR32 in two publications [386,1248]. The pairing was not replicated in a recent study based on arrestin recruitment [2218].…”

Section: Commentsmentioning

confidence: 94%

“…Searchable [825] -Mouse resolvin D1 [1248], LXA 4 [1248] -Labelled ligands -----[ 3 H]resolvin D1 (Agonist) [1248] -Comments Gene disruption results in increased severity of functional decompensation following aortic banding [13]. Identified as a susceptibility locus for osteoarthritis [613,1153,2410].…”

Section: Commentsmentioning

confidence: 99%

“…Chemerin 1 is also activated by the lipid-derived, anti-inflammatory ligand resolvin E1 (RvE1), which is formed via the sequential metabolism of EPA by aspirin-modified cyclooxygenase and lipoxygenase [69,70]. In addition, two GPCRs for resolvin D1 (RvD1) have been identified: FPR2/ALX, the lipoxin A 4 receptor, and GPR32, an orphan receptor [1248].…”

Section: Chemerin Receptorsmentioning

confidence: 99%

“…Brink C et al (2003) [907,1754,2299] 5-oxo-ETE, 5-oxo-C20:3, 5-oxo-ODE > 5-oxo-15-HETE > 5S-HPETE > 5S-HETE [792,975,1088,1756,1823,1898,2106] LXA 4 = aspirin triggered lipoxin A4 = ATLa2 = resolvin D1 > LTC 4 = LTD 4 15-deoxy-LXA4 fMet-Leu-Phe [427,641,643,805,2298] Endogenous agonists -----LXA 4 [1248], resolvin D1 [1248], aspirin-triggered resolvin D1 [1247], aspirin triggered lipoxin A4…”

Section: Further Reading On Leukotriene Receptorsmentioning

confidence: 99%

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THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors

Alexander

Christopoulos

Davenport

et al. 2021

British J Pharmacology

385

274

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The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (https://www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.15538. G protein‐coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.

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“…Resolvin D1 has been demonstrated to activate GPR32 in two publications [386,1248]. The pairing was not replicated in a recent study based on arrestin recruitment [2218].…”

Section: Commentsmentioning

confidence: 94%

Section: Commentsmentioning

confidence: 99%

Section: Chemerin Receptorsmentioning

confidence: 99%

Section: Further Reading On Leukotriene Receptorsmentioning

confidence: 99%

See 2 more Smart Citations

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors

Alexander

Christopoulos

Davenport

et al. 2021

British J Pharmacology

385

274

View full text Add to dashboard Cite

show abstract

“…eIF2-GTP delivers initiator methionyl transfer RNA to the small ribosomal subunit via a ternary complex of eIF2-GTP-Met-tRNA i ( 7). Mutations in the yeast eIF2B regulatory module weaken its binding to eIF2(αP), render eIF2B insensitive to eIF2(αP) inhibition, and impair the stress response mechanism ( 8). One possibility was that ISRIB also works by overcoming the ability of eIF2(αP) to inhibit eIF2B and thereby blocks the integrated stress response.…”

mentioning

confidence: 99%