Report of the 78th National Conference on Weights and Measures 1993

Brickenkamp, Carroll S.; Turner, Ann H

doi:10.6028/nist.sp.854

Cited by 3 publications

(6 citation statements)

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“…Global cognitive assessment was performed with the Montreal Cognitive Assessment adapted to age and education level (eTable 1 in the Supplement). Attention was assessed through the d2-R test . Memory complaint was assessed through the McNair self-questionnaire .…”

Section: Methodsmentioning

confidence: 99%

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Four-Month Clinical Status of a Cohort of Patients After Hospitalization for COVID-19

Morin

Savale

Pham

et al. 2021

JAMA

509

344

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The Writing Committee for the COMEBAC Study Group IMPORTANCE Little is known about long-term sequelae of COVID-19.OBJECTIVE To describe the consequences at 4 months in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTSIn a prospective uncontrolled cohort study, survivors of COVID-19 who had been hospitalized in a university hospital in France between March 1 and May 29, 2020, underwent a telephone assessment 4 months after discharge, between July 15 and September 18, 2020. Patients with relevant symptoms and all patients hospitalized in an intensive care unit (ICU) were invited for further assessment at an ambulatory care visit. EXPOSURES Survival of hospitalization for COVID-19.MAIN OUTCOMES AND MEASURES Respiratory, cognitive, and functional symptoms were assessed by telephone with the Q3PC cognitive screening questionnaire and a checklist of symptoms. At the ambulatory care visit, patients underwent pulmonary function tests, lung computed tomographic scan, psychometric and cognitive tests (including the 36-Item Short-Form Health Survey and 20-item Multidimensional Fatigue Inventory), and, for patients who had been hospitalized in the ICU or reported ongoing symptoms, echocardiography. RESULTS Among 834 eligible patients, 478 were evaluated by telephone (mean age, 61 years [SD, 16 years]; 201 men, 277 women). During the telephone interview, 244 patients (51%) declared at least 1 symptom that did not exist before COVID-19: fatigue in 31%, cognitive symptoms in 21%, and new-onset dyspnea in 16%. There was further evaluation in 177 patients (37%), including 97 of 142 former ICU patients. The median 20-item Multidimensional Fatigue Inventory score (n = 130) was 4.5 (interquartile range, 3.0-5.0) for reduced motivation and 3.7 (interquartile range, 3.0-4.5) for mental fatigue (possible range, 1 [best] to 5 [worst]). The median 36-Item Short-Form Health Survey score (n = 145) was 25 (interquartile range, 25.0-75.0) for the subscale "role limited owing to physical problems" (possible range, 0 [best] to 100 [worst]). Computed tomographic lung-scan abnormalities were found in 108 of 171 patients (63%), mainly subtle ground-glass opacities. Fibrotic lesions were observed in 33 of 171 patients (19%), involving less than 25% of parenchyma in all but 1 patient. Fibrotic lesions were observed in 19 of 49 survivors (39%) with acute respiratory distress syndrome. Among 94 former ICU patients, anxiety, depression, and posttraumatic symptoms were observed in 23%, 18%, and 7%, respectively. The left ventricular ejection fraction was less than 50% in 8 of 83 ICU patients (10%). New-onset chronic kidney disease was observed in 2 ICU patients. Serology was positive in 172 of 177 outpatients (97%).CONCLUSIONS AND RELEVANCE Four months after hospitalization for COVID-19, a cohort of patients frequently reported symptoms not previously present, and lung-scan abnormalities were common among those who were tested. These findings are limited by the absence of a control group and of pre-COVID assessments in this cohort. ...

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Section: Methodsmentioning

confidence: 99%

“…Attention was assessed through the d2-R test . Memory complaint was assessed through the McNair self-questionnaire . “Cognitive complaint” was defined by an impaired McNair score, reported cognitive symptoms, or both.…”

Section: Methodsmentioning

confidence: 99%

Four-Month Clinical Status of a Cohort of Patients After Hospitalization for COVID-19

Morin

Savale

Pham

et al. 2021

JAMA

509

344

View full text Add to dashboard Cite

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“…The reliability has proven to be very high, and the validity of the technique has been documented by a number of research studies (Brickenkamp, 2002;Flett, Madorsky, Hewitt, & Heisel, 2002). Norms are available based on representative German samples (Brickenkamp, 2002).…”

Section: Self-report and Neuropsychological Measuresmentioning

confidence: 99%

“…AN patients additionally completed the Eating Disorders Inventory II (Garner, 1991;Paul & Thiel, 2004) and the Three Factor Eating Questionnaire (Stunkard & Messick, 1985;German Version FEV, Pudel & Westenhöfer, 1989). To preclude alternative explanations for memory performance, attention (d2 Test of Attention, Brickenkamp, 1972Brickenkamp, , 2002 was assessed.…”

Section: Procedures and Designmentioning

confidence: 99%

“…It consists of 11 subscales measuring disordered eating behaviour and associated psychological characteristics: drive for thinness, bulimia, body dissatisfaction, ineffectiveness, perfectionism, interpersonal distrust, interoceptive awareness, maturity fears, asceticism, impulse regulation and social insecurity. The instrument shows high reliability and good validity, and norms are available for clinical and healthy populations.The d2 test (Brickenkamp, 1972(Brickenkamp, , 2002 measures processing speed, rule compliance and quality of performance, allowing for a neuropsychological estimation of individual attention and concentration performance. The reliability has proven to be very high, and the validity of the technique has been documented by a number of research studies (Brickenkamp, 2002;Flett, Madorsky, Hewitt, & Heisel, 2002).…”

mentioning

confidence: 99%

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Characteristics of Disorder‐Related Autobiographical Memory in Acute Anorexia Nervosa Patients

Huber

Salatsch

Ingenerf

et al. 2015

Euro Eating Disorders Rev

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Early life stress-induced miR-708-5p affects bipolar disorder-associated phenotypes through neuronatin downregulation

Gilardi,

Martins,

Bianco

et al. 2024

Preprint

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The underlying physiological and molecular mechanisms of bipolar disorder (BD) remain largely unknown. Here, by using unbiased small RNA sequencing in peripheral blood mononuclear cells (PBMCs), we found that miR-708-5p, a microRNA that was previously associated with BD, is the most strongly upregulated microRNA in peripheral blood of both healthy human subjects with a high genetic or environmental predisposition to develop mood disorders (MDs). Furthermore, miR-708-5p is strongly upregulated in patients diagnosed with BD and has potential in conjunction with the previously identified miR-499-5p to differentiate BD patients from patients suffering from major depressive disorder (MDD) and healthy controls. miR-708 is also upregulated in the hippocampus of wild type juvenile rats that underwent social isolation, as well as in juvenile rats heterozygous for the BD risk gene Cacna1c. Furthermore, ectopic overexpression of miR-708-5p in the hippocampus of adult male mice leads to BD-associated endophenotypes, such as reduced behavioral despair, enhanced compulsivity, and short-term memory impairments. miR-708-5p directly targets Neuronatin (Nnat), an endoplasmic reticulum (ER) resident protein involved in calcium homeostasis. Restoring Nnat expression in the hippocampus of miR-708-5p overexpressing mice rescues BD-associated endophenotypes. In summary, we functionally link miR-708-5p dependent regulation of Nnat to BD, with potential implications for BD diagnosis and therapy.

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Report of the 78th National Conference on Weights and Measures 1993

Cited by 3 publications

References 0 publications

Four-Month Clinical Status of a Cohort of Patients After Hospitalization for COVID-19

Four-Month Clinical Status of a Cohort of Patients After Hospitalization for COVID-19

Characteristics of Disorder‐Related Autobiographical Memory in Acute Anorexia Nervosa Patients

Early life stress-induced miR-708-5p affects bipolar disorder-associated phenotypes through neuronatin downregulation

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