The purpose of this paper is to prove Ein-Lazarsfeld's conjecture on asymptotic vanishing of syzygies of algebraic varieties. This result, together with Ein-Lazarsfeld's asymptotic nonvanishing theorem, describes the overall picture of asymptotic behaviors of the minimal free resolutions of the graded section rings of line bundles on a projective variety as the positivity of the line bundles grows. Previously, Raicu reduced the problem to the case of products of three projective spaces, and we resolve this case here.