We provide examples of abelian surfaces over number fields K whose reductions at almost all good primes possess an isogeny of prime degree ℓ rational over the residue field, but which themselves do not admit a K-rational ℓ-isogeny. This builds on work of Cullinan and Sutherland. When K = Q, we identify certain weight-2 newforms f with quadratic Fourier coefficients whose associated modular abelian surfaces A f exhibit such a failure of a local-global principle for isogenies.