“…The causes of model misspecification are numerous; for a comprehensive discussion, see Engelen et al (2002). The main ones are (i) flux-process dimension-reduction error (e.g., Kaminski et al, 2001), which is a consequence of using a spatio-temporal model for the flux field that is low-dimensional and inflexible; (ii) an inaccurate prior flux mean, variance, and covariance (e.g., Philip et al, 2019); (iii) transport-model errors (e.g., Houweling et al, 2010;Basu et al, 2018;Schuh et al, 2019) arising from the underlying assumed physics, meteorology, and discretisation schemes used (e.g., Lauvaux et al, 2019;McNorton et al, 2020); (iv) retrieval biases (e.g., O'Dell et al, 2018) and incorrect associated measurement-error statistics (e.g., Worden et al, 2017); and (v) measurement-error spatio-temporal correlations that are not fully accounted for (e.g., Chevallier, 2007;Ciais et al, 2010). Two other causes of model misspecification worth noting are an incorrectly specified initial global mole-fraction field, and flux components assumed known in the inversion (i.e., assumed degenerate at their prior mean), such as anthropogenic emissions (e.g., Feng et al, 2019).…”