Reproducibility of a four-point clinical severity score for glabellar frown lines

Abstract

The clinical 0-3 score for glabellar frown lines shows a good inter- and intraobserver reproducibility.

Treating Depression with Botulinum Toxin: A Pooled Analysis of Randomized Controlled Trials

“…Since the 2 versions are highly correlated (r = 0.82-0.94) and have an identical point range, we used them as one scale (BDI) [21]. All studies used the same Clinical Severity Score for Glabellar Frown Lines (CSS-GFL) to assess frown scores at baseline and week 6 [22]. One of the trials involved a cross-over of the BTA and the placebo group after 12 weeks.…”

Efficacy and Safety of 3- and 5-Injection Patterns (30 and 50 U) of Botulinum Toxin A (Dysport) for the Treatment of Wrinkles in the Glabella and the Central Forehead Region

“…The main efficacy assessments were based on a 4-point standardized clinical scale (0, no wrinkles; 1, mild wrinkles; 2, moderate wrinkles; and 3, severe wrinkles) that has been shown to have good to excellent reproducibility. 11 Unlike other studies [1][2][3] that have used 2 separate scales, only 1 scale was used to grade the wrinkles at maximum frown and at rest in this study.…”

The use of non‐invasive instruments in characterizing human facial and abdominal skin

“…However, in aesthetic medicine, differences can sometimes be subtle which can make clinically significant changes difficult to quantify. Clinicians and researchers alike have therefore sought objective ways to categorize changes in human skin [1][2][3][4][5][6][7][8]. Profilometry with facial molding, and semiobjective visual assessment scales [i.e., the Fitzpatrick perioral and periorbital wrinkle scoring system and the Wrinkle Severity Rating Scale (WSRS)] have emerged as useful tool to assess wrinkles and changes in wrinkle severity [1,2,4,9].…”