Reproductive factors in relation to ovarian cancer: a case–control study in Northern Vietnam

Le, Duc-Cuong; Kubo, Toshikazu; Fujino, Yoshihisa; Sokal, David C.; Vach, Trinh Huu; Pham, Truong-Minh; Matsuda, Shinya

doi:10.1016/j.contraception.2012.02.019

Cited by 19 publications

(27 citation statements)

References 35 publications

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“…Duration of oral contraceptive use among our study population may be insufficient to produce a protective effect, as only 32% of ever users consumed oral contraceptives for over 5 years. Increasing parity was also inversely associated with the ovarian cancer risk, consistent with several epidemiological studies [7-9,14,16,17,19] and a pooled analysis of 10 case-control studies from the United States [34]. …”

Section: Discussionsupporting

confidence: 85%

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Reproductive factors for ovarian cancer in southern Chinese women

Pasalich

Binns

et al. 2013

J Gynecol Oncol

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ObjectiveTo investigate the association between reproductive factors and the risk of ovarian cancer among southern Chinese women.MethodsA hospital-based case-control study was undertaken in Guangzhou, Guangdong Province, between 2006 and 2008. A structured questionnaire was used to obtain information on parity, oral contraceptive use and other reproductive factors in a sample of 500 incident ovarian cancer patients and 500 controls (mean age, 59 years). Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using unconditional logistic regression models.ResultsHigh parity was inversely associated with ovarian cancer, with an adjusted OR 0.43 (95% CI, 0.30 to 0.62) for women who had given birth to 3 or more children compared to women who had given no more than one birth. Ever use of oral contraceptives was also protective against ovarian cancer; adjusted OR 0.56 (95% CI, 0.40 to 0.78). No association was found for hormone replacement therapy, menopausal status, hysterectomy and family history of ovarian and/or breast cancer.ConclusionHigh parity and oral contraceptive use are associated with a lower risk of ovarian cancer in southern Chinese women.

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Section: Discussionsupporting

confidence: 85%

“…Long-term oral contraceptive use and higher parity are consistently associated with a reduced ovarian cancer risk [7-19]. Hysterectomy has been suggested to be protective, estimated to confer a 30%-50% risk reduction [20-23].…”

Section: Introductionmentioning

confidence: 99%

Reproductive factors for ovarian cancer in southern Chinese women

Pasalich

Binns

et al. 2013

J Gynecol Oncol

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“…In this study, we did not find a significant association between ever OC use or long duration of OC use and ovarian cancer risk. This is in agreement with other case–control studies conducted among Chinese or Asian women . The prevalence rate of OC use in China has remained relatively low, as compared with the rest of the world .…”

Section: Discussionsupporting

confidence: 91%

“…Further, IUD use among Chinese women has been shown to be long; a cross‐sectional survey found that >50% of postmenopausal IUD users had durations of use of >20 years . The underlying biologic mechanisms of IUD on ovarian cancer risk remain unclear, but a lowered ovarian cancer risk related to IUD use has been reported by several case–control studies conducted among Asian women . Although our analysis for ever versus never IUD use did not reach statistical significance, we did find that longer duration of IUD use was associated with lower ovarian cancer risk.…”

Section: Discussioncontrasting

confidence: 74%

Contraceptive methods and ovarian cancer risk among Chinese women: A report from the Shanghai Women's Health Study

et al. 2015

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Oral contraceptive (OC) use is associated with reduced ovarian cancer risk; however, associations with other contraceptive methods, such as intrauterine device (IUD) and tubal ligation (TL), are less clear. Women in China differ from western women in regard to mechanisms and duration of use of contraception. This study was undertaken to evaluate associations between contraceptive methods and ovarian cancer risk using data from the prospective Shanghai Women’s Health Study. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated by Cox proportional hazards regression. A total of 174 epithelial ovarian cancer cases were found to occur among 70,259 women that were followed for a total of 888,258 person years. The majority of women had ever used any contraception (77.0%), including IUD use (55.6%), OC use (20.4%), TL (14.7%), and contraceptive shots (2.6%). Ever use of any contraception was associated with a non-significant reduction in ovarian cancer risk (HR: 0.86, 95% CI: 0.60–1.24). Longer duration of IUD use was associated with lower ovarian cancer risk (P-value for trend=0.04). Compared to never users, women with durations of IUD use longer than the median (20 years) were 38% less likely to develop ovarian cancer (HR: 0.62, 95% CI: 0.40–0.97). Based on the high prevalence and long duration of IUD use among Chinese women, we estimate a preventive fraction of 9.3%, corresponding to approximately 16 ovarian cancer cases. High prevalence of long-term IUD use may therefore contribute to the low incidence of ovarian cancer observed in China.

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“…Based on the latest National Immunization Survey data in McLaughlin et al, 2007;Antoniou et al, 2009;Moorman et al, 2009;Jordan et al, 2010;Titus-Ernstoff et al, 2010;PermuthWey et al, 2011;Tsilidis et al, 2011;Jordan et al, 2012;Kurta et al, 2012;Le et al, 2012;Pieta et al, 2012;Weiderpass et al, 2012;Wilailak et al, 2012;Su et al, 2013). Some studies indicate that breastfeeding lowers risk of developing ovarian cancer (Risch et al, 1983;CSHS, 1987;Harlow et al, 1988;Gwinn et al, 1990;Whittemore et al, 1992;Siskind et al, 1997;Salazar-Martinez et al, 1999;Greggi et al, 2000;Modugno et al, 2001;Tung et al, 2003;Mills et al, 2004;Rossing et al, 2004;Huusom et al, 2006;McLaughlin et al, 2007;Moorman et al, 2009;Jordan et al, 2010;Titus-Ernstoff et al, 2010;Permuth-Wey et al, 2011;Jordan et al, 2012;Kurta et al, 2012;Pieta et al, 2012;Wilailak et al, 2012;Su et al, 2013), while many other studies observed no associations between breastfeeding and ovarian cancer risk (Mori et al, 1988;Booth et al, 1989;<...>…”

Section: Introductionmentioning

confidence: 99%

Breastfeeding and Ovarian Cancer Risk: a Systematic Review and Meta-analysis of 40 Epidemiological Studies

Li¹,

Du²,

Zhang³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Asian Pac J Cancer Prev, 15 (12), 4829-4837 IntroductionBreastfeeding is the most common method by which mothers provide nutrition to newborn infants. Based on the latest National Immunization Survey data in 2012, the overall rate of initiation of breastfeeding in the United States is 76.9% (CDC). The most significant effect of breastfeeding on maternal health is the reduced risk of developing breast cancer (Bernier et al., 2000; Collaborative Group on Hormonal Factors in Breast, 2002;do Carmo Franca-Botelho et al., 2012). Studies of the overall effect of breastfeeding on maternal outcomes also suggest that breastfeeding decreases the risk of developing hypertension, hyperlipidemia, cardiovascular disease and diabetes (Schwarz et al., 2009). Infant could also benefit from long-term breastfeeding, e.g. prevention of Childhood Hodgkin Lymphoma (Wang et al., 2013).Ovarian cancer is the sixth most common cancer and the seventh-leading cause of cancer-related deaths among women. The prognosis for ovarian cancer is poor, with a 5-year survival rate of less than 45% (Jemal et al., 2011), and the causes of the disease are not understood. There

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Reproductive factors in relation to ovarian cancer: a case–control study in Northern Vietnam

Cited by 19 publications

References 35 publications

Reproductive factors for ovarian cancer in southern Chinese women

Reproductive factors for ovarian cancer in southern Chinese women

Contraceptive methods and ovarian cancer risk among Chinese women: A report from the Shanghai Women's Health Study

Breastfeeding and Ovarian Cancer Risk: a Systematic Review and Meta-analysis of 40 Epidemiological Studies

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