In the cultural heritage field, heterogeneous materials and multicultural, multilingual user groups and their varying needs pose a challenge for information system design and its evaluation alike. Cultural heritage information systems can be evaluated from a system-centric or a user-centric perspective. This chapter discusses evaluation methods in digital libraries with a particular focus on cultural heritage collections and their distinctive features, interaction patterns, and challenges. It describes state-of-the-art evaluation methods illustrating them with examples from Europeana, the European portal for access to digital library, museum, and archive collections, and other projects from within the cultural heritage domain.