Research involving Human Subjects - Ethical Perspective

Abstract

Research involving human subjects are important to develop new therapeutics for the betterment of the human race. To take part in such research as volunteers is moral duty of any human. But such experiments should be justifiable and minimal risky for the participants. History of unethical research involving humans led to the development of many guidelines to make such research ethical as well as to gain maximum possible output. Several guidelines have been formulated to ensure research with human participants ethical. All the guidelines emphasize on one thing in particular- informed consent of the human subjects. Other considerations include rational benefit-harm ration, beneficence, justice, adequate research design and approval from proper authorities. All these guidelines aim to prevent any unethical research involving humans against their will. DOI: http://dx.doi.org/10.3329/bioethics.v4i2.16375 Bangladesh Journal of Bioethics 2013; 4(2) 41-48

Comparative evaluation of antimicrobial properties and phytochemical composition of Artocarpus altilis leaves using ethanol, n-hexane and water

“…The antimicrobial activity of seedless breadfruit using agar diffusion technique corresponds with the zone of inhibition range of 16.5 to 9 mm reported by Fakruddin et al (2012) against Gram positive B. subtilis using the same solvent (ethanol). Antimicrobial activity of seedless breadfruit leaves extracts using agar dilution technique showed that the ethanol extract had a higher inhibitory activity against the test organisms used for the analysis than the n-hexane and water extracts as compared to the two methods used for the antimicrobial analysis, agar dilution technique proved to be a better method as compared to the agar diffusion technique in the present study.…”