This paper presents a comprehensive review of research works on condensation and boiling heat transfer characteristics in horizontal, vertical and inclined tubes both smooth and enhanced. Although there are many studies examining two-phase flows inside tubes, it is almost impossible to find such a comprehensive study for two-phase flow in tubes. Moreover, while number of the studies concerning condensation or boiling inside tubes are limited, the present study covers almost all studies of condensation and boiling inside inclined tubes. Previous studies are classified into many subtitles according to configuration (horizontal, vertical or inclined) and roughness (smooth or enhanced) as well as aim of the study (researching the effect of parameters on the heat transfer coefficient, pressure drop or evaluation of prediction correlation). Such a wide range of classification and scope have no done before. Condensation and boiling phenomena are of great importance in heat exchangers, cooling systems, etc. due to their wide utilization in those devices. Additionally, two-phase flow and the associated heat transfer are becoming increasingly important in industrial applications because the heat transfer coefficient in twophase flows is much higher than in single-phase flows. In this research, major topics such as heat transfer, pressure drop, friction factor and void fraction were studied using active and passive techniques in the literature. The fluids used in the reviewed studies diverse in a very wide range. For pure refrigerants (single component-fluorocarbon refrigerant),