Two non-quenched and tempered (NQT) prehardened plastic mould steels, differing by titanium content, were produced to have good hardness uniformity in large sections (485 × 970 and 465 × 1325 mm 2 ). The effect of titanium on continuous cooling transformation curves, hardness uniformity and microstructure (grain size, phase constituents) were studied. It was found titanium had refined the grain size of NQT steel by the pinning effect of Ti (C, N) at grain boundaries, and titanium also effectively postponed the nucleation of proeutectoid ferrite in intercritical region. Using finite element method, the cooling rate from core to surface along longitude direction of the steels was predicted. The results indicated that the NQT steel with titanium had better process adaptability than that of NQT steel without titanium. Compared with production of NQT steel without titanium, production for NQT steel with titanium can largely save the production cost by shortening the production cycle and reducing the resources.