With the rapid development of modern technology and the economy, the global value chain is also constantly evolving, and the links between various industries are becoming closer. With the continuous optimization of the international situation and the support of Chinese policies, the integrated development of manufacturing and service industries is the general trend. This study proposes to use human-computer interaction to conduct in-depth research and analysis of the development relationship, influencing factors, and evolution direction between manufacturing and service industries in the perspective of deep learning. Firstly, based on the current development status of the two industries, the influencing factors of mutual evolution are summarized, including environment, market, technology, and management. Secondly, the computer is used to construct the evolution models of the two major industries. The simulation verification and evolution feature extraction are carried out.