SummaryThis research deals with a frame‐supported shear wall for urban over‐track building of vehicle depot in Chisha, Guangzhou, China, which is characterized by its remarkable height of 160.8 m. Technical issues are commonly encountered in these kinds of buildings due to discontinuous vertical structural rigidity, large podium, and structural transition. These challenges significantly impact the engineering process, especially when the rigidity difference between transfer story exceeding the threefold, as well as the building height exceeds limit as in code. In this paper, a shaking table test was developed based on a 1:10 scaled model of the structure. Using similarity theory, the dynamic similarity relationship was established for the design of the model. Subsequently, the experimental model was constructed with the configuration of critical parameters such as mass design, sensor placement, and seismic test conditions. This was followed by in‐depth analysis, recording component failures and investigating key aspects such as dynamic characteristics, that is, acceleration and displacement responses and shear force distribution under different earthquake intensities. A theoretical seismic response of the prototype structure was derived from the test results. The shaking table tests confirmed that the structure met the stringent seismic design requirements as prescribed in the Chinese standards, with no damage under minor earthquakes, repairability under moderate earthquakes, and collapse prevention under rare earthquakes. The results of the study provide valuable insights along with improvement measures for the design and development of similar urban over‐track buildings, potentially contributing to more efficient land use in urban China.