The seed metering device construction is adjusted to improve the negative pressure at the seed metering device type hole and hence the seed suction efficiency. To explore the link between the structural parameters of the seed metering device and the negative pressure of the type hole, the Response Surface Methodology (RSM) is integrated with Computational Fluid Dynamics (CFD). Grid independence was tested to assure the solution's dependability. The internal flow field of the seed metering device was investigated, and the negative pressure at the type hole's input was 56.71 Pa. The Central Composite Design (CCD) in the response surface method was employed to generate a more perfect negative pressure at the suction of the type hole. The diameter of the air chamber channel, the draft angle of the type hole, and the number of fan blades were employed as design factors, and the major target function was the negative pressure at the entrance of the type hole. According to regression research, the optimal point occurs when the air chamber channel diameter is 59.26mm, the draft angle of the type hole is 14.28°, and the number of fan blades is 9. The objective function predicts a negative pressure of 69.41 Pa at the type hole's inlet. The Central Composite Design (CCD) in the response surface method was employed to generate a more perfect negative pressure at the suction of the type hole. The diameter of the air chamber channel, the draft angle of the type hole, and the number of fan blades were employed as design factors, and the major target function was the negative pressure at the entrance of the type hole. According to regression research, the optimal point occurs when the air chamber channel diameter is 59.26mm, the draft angle of the type hole is 14.28°, and the number of fan blades is 9. The objective function predicts a negative pressure of 69.41 Pa at the type hole's inlet.