PurposeThe present study aims to trace out the science research output of top Indian universities from 2015 to 2019, as reflected in the Web of Science (WOS) database.Design/methodology/approachThe present study has selected the Science Citation Index (SCI) of WOS core collection for selecting top Indian universities in terms of total publications in the last five years (2015–2019). The University of Delhi (DU), Banaras Hindu University (BHU), Anna University (AU), Jadavpur University (JU) and Punjab University (PU) have been selected. The study identified the most prolific authors, collaborating countries, collaborating institutions and the impact of their output in terms of citations per paper (CPP) and relative citation impact (RCI). For visualizing purposes, VOSviewer was used. The study also identified frequently used keywords and channels used for communicating research results.FindingsThe authors retrieved 26,173 documents consisting of journal articles, review papers and proceeding papers. The consistent growth of science research output has been observed. The University of Delhi (DU) has the maximum science publications. The study reflects that multi-authored papers have more research impact in terms of citation received. The USA, South Korea and Germany are the most collaborating countries. The top Indian Universities have a major collaboration with Anna University, Indian Institute of Technology, Center for Scientific and Industrial Research (CSIR) of India.Originality/valueThe present study reveals how the science research output of top Indian universities has grown in the last few years. The findings of the study can be used for identifying specific science research areas where special attention can be given.