Residual Lung Abnormalities after COVID-19 Hospitalization: Interim Analysis of the UKILD Post–COVID-19 Study

Lung parenchymal abnormalities and outcomes in hospitalized patients with COVID 19 pneumonia: A positive message from a prospective hospital-based longitudinal study for future considerations

“…[ 1 , 2 ] Our factual observations at 4–8 weeks interpreted prospectively in a precise manner based on pre specified criteria are in keeping with the interim analyses of the UKILD Post-COVID study that estimated residual lung abnormalities in up to 11% of people following COVID-19 related hospitalization. [ 7 ] In essence, our findings confirms the estimate from the UKILD study and are complementary.…”

Radiologic Findings after COVID-19 and the Correlation with Lung Function

“…The term “long COVID” became widely known in society and dedicated studies were proposed. These studies are demonstrating the long-term findings in COVID-19 [ 5 ], as well as the changing pattern of disease with the effects of vaccine programs and new variants [ 6 , 7 ]. Clearly, the imaging findings are evolving and must be evaluated in the context of clinical symptoms.…”

Persistence of a SARS-CoV-2 T-cell response in patients with long COVID and lung sequelae after COVID-19

“…Most individuals fully recover after suffering coronavirus disease 2019 (COVID-19), but a subset of patients present persistent post-disease abnormalities, including: 1) long COVID, defined as the persistence (>2 months) of symptoms 3 months after the onset of COVID-19 that cannot be explained by an alternative diagnosis 1 ; and 2) chronic pulmonary sequelae, defined as abnormal lung function and/or lung structure [2][3][4][5] . The mechanisms underlying long COVID or pulmonary sequelae remain unknown, but both have been associated with persistent inflammation 6,7 , including alterations in the blood CD8+ T cells and a sustained virus specific T cell response [8][9][10] .…”