Abstract. In this paper, welding induced residual stresses in a welded API 5L X65 girth pipe spools are discussed in as-welded and in local post weld heat treated conditions. Stress measurements were carried out non-destructively using the neutron diffraction technique. For such large-scale components residual stress measurements require significant preparation and planning. First of all, a choice of stress free lattice spacing value, discussed extensively, is of great importance for the evaluation of residual strains and stresses correctly. Besides, the use of a virtual instrument (SSCANSS software) can optimize measurements for distorted or undistorted large components with or without complex details. Moreover, the well-planned "window" cut through the thickness greatly reduced measurement time. A number of points were measured across the weld, HAZ and the parent material. Measurement results showed that residual stresses in the as-welded condition was lower than the yield strength of the material, and significant relaxation was also observed in the post weld heat treated samples.