Residue analysis of tetracyclines in milk by HPLC coupled with hollow fiber membranes-based dynamic liquid-liquid micro-extraction

Xu, Hui; Mi, Hongyu; Guan, Mingming; Shan, Hongyan; Fei, Qiang; Huan, Yanfu; Zhang, Zhiquan; Feng, Guodong

doi:10.1016/j.foodchem.2017.04.021

Cited by 90 publications

(23 citation statements)

References 16 publications

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“…The acceptor solvent was 0.1 M phosphoric acid, 1.0 M sodium chloride with pH = 1.6, 0.05 M disodium hydrogen phosphate (pH between 9.1 and 9.5) containing the sample as the donor phase and 10% (w/v) of Aliquat-336 in octanol as a SLM. The LOD and LOQ were 0.5-1.0 and 0.5-1.0 μg L −1 respectively which are lower compared to the ones obtained by Xu et al [38] proving that fiber membranebased dynamic liquid-liquid microextraction is a more efficient extraction method. All the milk samples contained TCs in the range of 6.0-27.4 μg L −1 that was below the MRL as set by the EU.…”

Section: Hollow Fiber Liquid Phase Microextractioncontrasting

confidence: 58%

“…Promising extraction and pre-concentration techniques for veterinary drug residues that have been explored recently by many researchers include dispersive liquid-liquid microextraction (DLLME) [5,6,35,36], hollow fiber based liquidphase microextraction (HFLPME) [37][38][39][40] and quick, easy, cheap, effective, rugged and safe (QuEChERS) [4, [41][42][43] where the general trend is compliance with green chemistry principles. Veterinary drug residues occur at trace levels as low nanogram per gram [4,37] hence the need to pre-concentrate.…”

Section: Pre-concentration Techniquesmentioning

confidence: 99%

“…The development of HFLPME provides a way to stabilize the extraction droplet in SD-LPME by placing it in a hollow fiber [54]. The main consumable material is the hollow fiber membrane, which is lower than other methods in cost and sample consumption [38]. The different modes of HFLPME are static, dynamic, two and three phase.…”

Section: Hollow Fiber Liquid Phase Microextractionmentioning

confidence: 99%

“…Xu et al [38] employed a carrier mediated three phase hollow fiber membrane based dynamic liquid-liquid microextraction coupled with HPLC-UV detection for the residue analysis of TCs in milk samples without deproteinization and defatting, but the milk samples were diluted five folds. A peristaltic pump was used to promote mass transfer between the carrier and the operated solution.…”

Section: Hollow Fiber Liquid Phase Microextractionmentioning

confidence: 99%

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Modern Extraction and Cleanup Methods of Veterinary Drug Residues in Food Samples of Animal Origin

Moyo¹,

Tavengwa²

2019

Recent Advances in Analytical Chemistry

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Extensive research on the presence of veterinary drug residues in food samples has been conducted and is still underway. The inappropriate or excessive use of veterinary drugs in food producing animals may result in trace quantities of these drugs or their metabolites in food samples. Food contamination by veterinary drug residues is one of the main challenges worldwide to public health with drug resistance being the biggest threat. One of the challenges in veterinary drug residue analysis is their occurrence in trace amounts that are normally below limits of detection of most analytical instruments. Various efficient, economical, miniaturized and environmentally friendly extraction methods have been developed in recent years to pre-concentrate these analytes before instrumental analysis to enhance their detection and also to overcome the limitations of traditional extraction methods such as liquid-liquid extraction and solid phase extraction. These methods include quick, easy, cheap, effective, rugged and safe (QuEChERS), molecularly imprinted polymers, dispersive liquid-liquid microextraction and hollow fiber liquid-phase microextraction, and they will be discussed in this chapter.

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Section: Hollow Fiber Liquid Phase Microextractioncontrasting

confidence: 58%

Section: Pre-concentration Techniquesmentioning

confidence: 99%

Section: Hollow Fiber Liquid Phase Microextractionmentioning

confidence: 99%

Section: Hollow Fiber Liquid Phase Microextractionmentioning

confidence: 99%

See 2 more Smart Citations

Modern Extraction and Cleanup Methods of Veterinary Drug Residues in Food Samples of Animal Origin

Moyo¹,

Tavengwa²

2019

Recent Advances in Analytical Chemistry

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show abstract

“…The proposed analytical method presented good performance when compared with other methods recently published as shown in S9. The obtained LOQs and LODs were equal or even lower.…”

Section: Resultsmentioning

confidence: 73%

Graphene particles supported on silica as sorbent for residue analysis of tetracyclines in milk employing microextraction by packed sorbent

et al. 2018

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This paper describes the use of graphene-based sorbents for determination of four tetracyclines in milk. The synthesized materials were combined with microextraction by packed sorbent (MEPS) to act as the sample preparation step. The extraction performance of these sorbents was compared to commercial phases, and graphene supported on silica provided the best results. The analytical method optimization was carried out by employing experimental design. Firstly, an evaluation of the experimental variables (elution solvent, use of EDTA, ionic force, and pH of the washing solution) was made by a 2 factorial experimental design. The variables sampling, washing and elution cycles of MEPS were further optimized under a full 2 experimental design. The validation parameters were determined under optimized conditions resulting in a linearity ranging from 15 to 110 μg/L with R values above 0.98, and LOQs ranging from 0.05 to 0.9 μg/L. The accuracy ranged from 87.9 to 118.4% and intra/inter-day precision reported by the RSDs were lower than 19%. The proposed and validated method was successfully applied to the analysis of 11 milk samples from different animals, revealing traces of tetracyclines in only two of them. This study focused on the evaluation of graphene-based sorbents combined with MEPS for tetracycline analysis provided equivalent or even better results than other proposed methods, suggesting being a sensitive, fast and reliable alternative method for the determination of tetracyclines in milk samples.

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Core–Shell ZIF‐8@ZIF‐67‐Derived Cobalt Nanoparticles In Situ Grown on N‐doped Carbon Nanotube Polyhedra for Ultrasensitive Electrochemical Detection of Chloramphenicol

Yang

Shao

et al. 2022

ChemElectroChem

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In this work, we developed a highly selective detector towards the antibiotic drug chloramphenicol (CAP) using Co nanoparticle, which are grown in situ on N‐doped carbon nanotube polyhedra (Co@NCNP), which are obtained by a pyrolysis strategy derived from core‐shell ZIF‐8@ZIF‐67. Physical characterization verified that metal‐organic framework (MOFs)‐derived Co@NCNP nanocomposites present a nanotube structure on their mesoporous polyhedron surface. As a result, the as‐prepared Co@NCNP can be used as a sensitive electrochemical sensor for chloramphenicol detection, and the modified electrode is also studied by electrochemical methods such as electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV), and differential pulse voltammetry (DPV). When compared with single ZIF‐67‐derived electrode, the Co@NCNP displays a higher electrocatalytic activity in the presence of chloramphenicol. Moreover, an excellent performance with a linear response range of 5–268.83 μM and a low detection limit of 0.5 μM (S/N=3) is observed for the Co@NCNP modified electrode. Finally, the fabricated chloramphenicol sensor achieves a good anti‐interference ability, stability, excellent repeatability, and remarkable reproducibility. The sensor also could be applied in human serum to determine of chloramphenicol with a satisfactory result.

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Residue analysis of tetracyclines in milk by HPLC coupled with hollow fiber membranes-based dynamic liquid-liquid micro-extraction

Cited by 90 publications

References 16 publications

Modern Extraction and Cleanup Methods of Veterinary Drug Residues in Food Samples of Animal Origin

Modern Extraction and Cleanup Methods of Veterinary Drug Residues in Food Samples of Animal Origin

Graphene particles supported on silica as sorbent for residue analysis of tetracyclines in milk employing microextraction by packed sorbent

Core–Shell ZIF‐8@ZIF‐67‐Derived Cobalt Nanoparticles In Situ Grown on N‐doped Carbon Nanotube Polyhedra for Ultrasensitive Electrochemical Detection of Chloramphenicol

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