Residue determination of Landrin insecticide by trifluoroacetylation and electron-capture gas chromatography

Abstract

A glc electron-capture method has been developed to measure nanogram amounts of Landrin insecticide and related carbamates after their reaction with trifluoroacetic anhydride. Concentrations of Landrin as low as 0.02 ppm in corn can be measured by this simple procedure. The trifluoroacetylated carbamates can be separated from one another on a 6-ft column packed with Gas Chrom Q coated with

N-Perfluoroacyl derivatives for methylcarbamate analysis by gas chromatography

“…The results indicate that two factors, solvent polarity and temperature, govern the rate of reaction and suggest three conditions for practical use: ethyl acetate at room temperature for 16 hr or more (the procedure of Lau and Marxmiller, 1970); ethyl acetate at 55°C for 2 hr; and benzene at 100°C conditions described, electron-capture background was consistently lower using the third method. Choice of conditions for a particular application, however, will depend on the type of sample (residue or formulation), detection system employed, and interferences generated from the sample substrate, particularly in residue analyses.…”

Residue determination of dichlorvos and related metabolites in animal tissue and fluids

“…Such conversions to trifluoroacetyl derivatives have previously been adapted to the analyses of amines and amino acids. More recently, Lau and Marxmiller (1970) converted carbamic acid esters to electron-capturing derivatives through use of trifluoroacetic anhydride. This paper describes procedures for processing samples of body tissue and fluids for residue analyses of dichlorvos and four possible metabolites.…”

On-Line High-throughput ESIMS Detection of a Reaction Product Using Synthesis and Extraction Microchips

“…By reducing the ionization hindrance, qualitative ESIMS detection of the products in a complex reaction mixture might become possible. With regard to Ntrifluoroacetylation of 2-phenetylamine as a model reaction, which is useful to protect of a hydroxyl group and/or an amino group for gas chromatographic analysis of non-volatile compounds, 27) on-chip synthesis, purification and on-line high-throughput and qualitative MS detection of products were investigated.…”