Residues and Dietary Risk Assessments of 2,4-D Isooctyl Ester, Metribuzin, Acetochlor, and 2-Ethyl-6-methylaniline in Corn or Soybean Fields

Zheng, Xutian; Liu, Chaolun; Hu, Jiye

doi:10.1021/acs.jafc.0c00193

Cited by 14 publications

(5 citation statements)

References 30 publications

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“…Subsequently, the properties of the absorbent used in the purification step were also evaluated. The tea matrix contained many interfering substances such as pigments, alkaloids, sterols, polyphenols and moisture 32,33 . Therefore, several purification agents were investigated to remove these substances in the complex matrix, including PSA, C 18 , graphitized black carbon (GCB) and MWCNTs.…”

Section: Resultsmentioning

confidence: 99%

“…The tea matrix contained many interfering substances such as pigments, alkaloids, sterols, polyphenols and moisture. 32,33 Therefore, several purification agents were investigated to remove these substances in the complex matrix, including PSA, C 18 , graphitized black carbon (GCB) and MWCNTs. The results showed that the initial recoveries of the target analytes in tea shoots and made tea samples were 73.5-91.8% and 77.8-83.2%, respectively, when using 50 mg GCB, whereas they were 53.6-72.8% and 47.6-79.1% when using C 18 separately.…”

Section: Resultsmentioning

confidence: 99%

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Residue analysis, dissipation patterns of chlorfenapyr, diafenthiuron and their corresponding metabolites in tea trees, and dietary intake risk assessment

et al. 2022

J Sci Food Agric

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BACKGROUND: Recently, chlorfenapyr and diafenthiuron have been widely used to prevent and control diseases and pests in tea production. However, rare studies have investigated the dissipation patterns of chlorfenapyr, diafenthiuron and their metabolites simultaneously in tea matrices. Here, we established an analytical method to investigate the degradation patterns of five target compounds in tea shoots and made tea samples. Moreover, the dietary intake risk assessment of chlorfenapyrdiafenthiuron mixture among Chinese populations was evaluated based on the supervised field experiment.RESULTS: The mean recoveries of the primary analytes at five spiking levels were between 95.6% and 112.6% in tea shoots and made tea, respectively, and the values of RSD (relative standard deviation) were lower than 9.7% for all the target analytes. The field trial results showed that the half-lives of chlorfenapyr and diafenthiuron based on the residue definition were 10.0-12.4 days and 4.3-5.9 days, respectively, in tea shoots. For the dietary intake risk assessment, the risk quotient (RQ) values in made tea ranged from 30.4% to 73.9% at the pre-harvest interval of 14 days, which were significantly less than 100%.CONCLUSION: The accuracy and precision of the developed method were satisfied by the measurement requirements according to the validation results. The dynamic dissipation experiments suggested that diafenthiuron was much easier to dissipate than chlorfenapyr. Moreover, the existence of tralopyril made the half-life of chlorfenapyr significantly increase, indicating that practical application of chlorfenapyr should take careful consideration of its metabolite. Finally, the potential chronic dietary risks of the chlorfenapyr-diafenthiuron mixture to human communities were within the acceptable range.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Residue analysis, dissipation patterns of chlorfenapyr, diafenthiuron and their corresponding metabolites in tea trees, and dietary intake risk assessment

et al. 2022

J Sci Food Agric

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“…The formulas to calculate NEDI and RQ are as follows where STMR i (mg/kg) is the median of the surveillance test of the pesticide residues in food registered in China, F i (kg) is the average daily intake of a certain food in China, and bw is the average body weight of the population subgroups. The ADI values are from GB 2763-2021…”

Section: Methodsmentioning

confidence: 99%

Dissipation, Residue, and Dietary Risk Assessment of Bifenthrin, Bifenazate, and Its Metabolite Bifenazate–Diazene in Apples Based on Deterministic and Probabilistic Methods

Zhao

Chai

Liu

et al. 2021

J. Agric. Food Chem.

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A rapid, sensitive, and effective multiresidue analytical method was established to investigate the degradation rate and final residues of bifenthrin, bifenazate, and its metabolite bifenazate–diazene in apples, and the dietary risk of consumers was evaluated. The residues of bifenthrin, bifenazate, and bifenazate–diazene in apple samples from 12 different apple-producing areas of China were determined by high-performance liquid chromatography tandem mass spectrometry (LC-MS/MS). The average recoveries of the three compounds in apples were 88.4–104.6%, and the relative standard deviations (RSDs) were 1.3–10.5%. The limit of quantification (LOQ) for each compound was 0.01 mg/kg. Although the degradation half-lives of bifenthrin, bifenazate, and bifenazate–diazene were 17.8–28.9, 4.3–7.8, and 5.0–5.8 days, under good agricultural practice (GAP) conditions, the final residues of bifenthrin, bifenazate, and the sum of bifenazate and its metabolite bifenazate–diazene in apples were <0.01–0.049, < 0.01–0.027, and <0.02–0.056 mg/kg, respectively, which were lower than the maximum residue limit (MRL) in China. By comparing the deterministic model with the probabilistic model, the results of the probabilistic model at the P95 level (12.91–48.9% for bifenthrin, 17.48–52.01% for bifenazate including its metabolite) were selected as reasonable assessment criteria for chronic dietary risk, and the acute risk was at the P99.9 level (3.00–15.59% for bifenthrin). Although the exposure risk calculated by both the deterministic model and the probabilistic model was less than 100%, the risk to children is significantly higher than that of the general population. This suggests that in future research and policy making, we should pay more attention to the risk of vulnerable groups such as children.

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“…The chronic dietary intake risks of BIF, DIN, DN and UF were calculated as follows (Zheng et al, 2020):

NEDI goodbreak= \sum ((), {STMR}_{i} goodbreak\times F_{i})

{RQ}_{c} goodbreak= \frac{NEDI}{ADI \times normalb . normalw .} goodbreak\times 100 %

where STMR i is the median residue value from supervised field trials (mg kg −1 ) and i represents different foods; F i (kg) represents the dietary intake of certain kinds of food used to plan and assess nutrient intakes of healthy Chinese people; NEDI is the national estimated daily intake of pesticide based on the Chinese dietary pattern (mg kg −1 , b.w. ); ∑ represents the sum of the NEDI of bifenthrin or dinotefuran in wheat or other regulated crops in China, since all registered crops should be taken into account in chronic dietary risk assessments; b.w.…”

Section: Methodsmentioning

confidence: 99%

“…The RQ c is the chronic risk quotient. If RQ c is >100%, the assessed crop caused an unacceptably high health risk for consumers; otherwise, the risk was minor (X. Li, Chen, & Hu, 2019; Nougadère et al, 2014; Zheng et al, 2020).…”

Section: Methodsmentioning

confidence: 99%

Residual levels and dietary risk assessment of bifenthrin and dinotefuran and its major metabolites in open wheat field conditions

2021

Biomedical Chromatography

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To evaluate the residual levels of bifenthrin and dinotefuran, a modified quick, easy, cheap, effective, rugged, and safe (QuEChERS) and high‐performance liquid chromatography–tandem mass spectrometry method for simultaneous detection of bifenthrin and dinotefuran and its major metabolites in wheat was developed and validated. Dietary risk assessments were further performed based on the relevant residual data from 12 wheat fields, toxicology data and dietary patterns. In wheat grain and straw, the recoveries of all analytes ranged from 77 to 102% with the relative standard deviation <9.7% and the limit of quantitation 0.05 mg kg−1. The highest terminal residue of bifenthrin in wheat grain was 0.069 mg kg−1 and dinotefuran was 0.34 mg kg−1. Residual concentrations of bifenthrin and dinotefuran decreased to <0.05 and 0.15 mg kg−1 at 21 days (pre‐harvest interval), respectively. The chronic risk quotient ranged from 6.4 to 62.7% and the acute risk quotient varied from 0.38 to 17.73%. The chronic and acute dietary risks caused by the terminal residues of the two insecticides were negligible for Chinese populations. The recommended pre‐harvest interval was proposed to ensure safe wheat consumption. These data could provide a scientific reference to establish the Chinese maximum residue limit of dinotefuran in wheat.

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Residues and Dietary Risk Assessments of 2,4-D Isooctyl Ester, Metribuzin, Acetochlor, and 2-Ethyl-6-methylaniline in Corn or Soybean Fields

Cited by 14 publications

References 30 publications

Residue analysis, dissipation patterns of chlorfenapyr, diafenthiuron and their corresponding metabolites in tea trees, and dietary intake risk assessment

Residue analysis, dissipation patterns of chlorfenapyr, diafenthiuron and their corresponding metabolites in tea trees, and dietary intake risk assessment

Dissipation, Residue, and Dietary Risk Assessment of Bifenthrin, Bifenazate, and Its Metabolite Bifenazate–Diazene in Apples Based on Deterministic and Probabilistic Methods

Residual levels and dietary risk assessment of bifenthrin and dinotefuran and its major metabolites in open wheat field conditions

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