Resistance to activated protein C in newborns with necrotizing enterocolitis

Göpel, Wolfgang; Christiansen, Bärbel; Möller, J.; Gortner, Ludwig

doi:10.1007/s004310051159

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Coagulation Disturbances Pathophysiology Of Coagulation Dist1

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2003

2022

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Cited by 4 publications

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“…In a study of 33 infants with NEC, the incidence of activated protein C resistance in the NEC children was similar to controls matched for gestational age, weight, and illness severity. 40 …”

Section: Coagulation Disturbances Pathophysiology Of Coagulation Distmentioning

confidence: 99%

Hematologic Abnormalities in Severe Neonatal Necrotizing Enterocolitis: 25 Years Later

Kling

Hutter

2003

J Perinatol

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Necrotizing enterocolitis (NEC), the most common surgical emergency in newborns, remains a therapeutic challenge for clinicians. The hematological manifestations associated with NEC were first described 25 years ago. This review discusses current knowledge of the pathophysiology involved in disturbances in megakaryocytopoiesis, coagulation, leukopoiesis, and erythropoiesis that accompany the clinical entity NEC. The discussion includes current understanding of and potential strategies for treating the hematopoietic disturbances that occur secondary to NEC.

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Section: Coagulation Disturbances Pathophysiology Of Coagulation Distmentioning

confidence: 99%