Resistance training decreases plasma levels of adipokines in postmenopausal women

Ward, Liam J.; Nilsson, Sigrid; Hammar, Mats; Lindh-Åstrand, Lotta; Berin, Emilia; Lindblom, Hanna; Holm, Anna‐Clara Spetz; Rubér, Marie; Li, Wei

doi:10.1038/s41598-020-76901-w

Cited by 21 publications

(28 citation statements)

References 55 publications

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“…Ward et al. 57 showed a significantly decreased plasma adiponectin in postmenopausal women and elevation after 15 weeks of RT engagement. Also, de Mello et al.…”

Section: Introductionmentioning

confidence: 98%

Exercise training modulates adipokine dysregulations in metabolic syndrome

Babaei

Hoseini

2022

Sports Medicine and Health Science

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“…Ward et al. 57 showed a significantly decreased plasma adiponectin in postmenopausal women and elevation after 15 weeks of RT engagement. Also, de Mello et al.…”

Section: Introductionmentioning

confidence: 98%

Exercise training modulates adipokine dysregulations in metabolic syndrome

Babaei

Hoseini

2022

Sports Medicine and Health Science

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“…We identified two ongoing studies (Supplemental Digital Content 3, http://links.lww.com/MENO/ B29). Therefore, 12 RCTs (reported in 16 references) [26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41] were included (Fig. 1).…”

Section: Search Resultsmentioning

confidence: 99%

Resistance training for postmenopausal women: systematic review and meta-analysis

et al. 2022

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Importance: Numerous studies have been published assessing the effects of resistance muscle training to mitigate menopausal symptoms, given the endocrine muscle function and its metabolic regulation. Therefore, mapping and synthesizing high-quality studies are necessary to help clinical decisions.Objective: The aim of this study was to assess the effects (benefits and harms) of resistance muscle training for postmenopausal women.Evidence Review: Electronic searches were conducted in MEDLINE (via PubMed), EMBASE, CENTRAL, PEDro, LILACS, and SPORTDiscus up to December 2021. Two independent reviewers selected the retrieved references and extracted relevant data from included studies. The methodological quality (risk of bias) using the Cochrane Risk of Bias table and the certainty of the evidence (GRADE approach) were assessed.Findings: Twelve randomized clinical trials (n = 452) with unclear to high risk of bias were identified. Compared with no exercise, resistance training (up to 16 weeks) seems to promote an improvement in functional capacity (mean difference [MD], 2.90 points; 95% CI, 0.60-5.20) and bone mineral density (MD, 0.10; 95% CI, 0.10-0.10) and a reduction in the hot flash frequency (13/29 vs 1/29; risk ratio, 13.0; 95% CI, 1.82-93.01) and fat mass (MD, −3.15; 95% CI, −6.68 to 0.38), and no differences were observed between groups regarding abdominal circumference and body mass index. When compared with aerobic exercises, resistance training may result in a reduction of hot flash frequency (7/ 18 vs 14/18; risk ratio, 0.50; 95% CI, 0.27-0.94) and fat mass (MD, −7.80; 95% CI, −14.02 to −1.58) and no difference in the quality of life and body mass index. Regarding safety, no serious adverse events were reported. Based on the GRADE approach, the certainty of this evidence was graded as very low to low, leading to imprecisely estimated effects.Conclusions and Relevance: Resistance muscle training seems to improve postmenopausal symptoms and functional capacity. Given the low to very low certainty of the evidence, further randomized clinical trials with higher methodological quality and better reports are still needed. As an implication for clinical practice, health professionals should consider individualized aspects such as the previous history of exercise practice, physical capacity, and adaptation period.

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“… 45 Likewise, Ward et al. 35 observed no change in leptin after 15 weeks of RT, Prestes et al. 45 observed a significant decrease in leptin after 16 weeks of RT (see Table 2 ).…”

Section: Resistance Training Intervention Length and Protocolmentioning

confidence: 93%

“…Also, there was a reduction in adiponectin and resistin after the RT intervention in both studies. 35 , 45 …”

Section: Resistance Training Intervention Length and Protocolmentioning

confidence: 99%

“… 32 , 33 In PMP women, the influence of aerobic exercise and RT and/or a combination of the two, has been investigated to evaluate the impact of decreasing AT. 34 , 35 Aerobic exercise training of various modalities (e.g., continuous intervals) can successfully reduce AT by 1%–7% in PMP while positively altering adipokine concentrations in a significant manner depending on the intervention length. 36 , 37 However, higher-intensity aerobic exercise produces greater oxidative stress in comparison to lower-intensity aerobic exercise, adding to the already elevated chronic inflammatory state of overweight and obese PMP women and potentially overwhelming cellular antioxidant capabilities.…”

Section: Introductionmentioning

confidence: 99%

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