Resolution of giant<i>Molluscum contagiosum</i>with antiretroviral therapy

Sen, Sumit; Bhaumik, Parna

doi:10.4103/0378-6323.41382

Cited by 12 publications

(6 citation statements)

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“…Multiple MC in HIV patients is intractable and resistant to standard therapies, including curettage. 2 Similar to our case, there are several reports that multiple MC in HIV patients have been improved by ART, 4 suggesting that the improvement of immunosuppressive state may be essential for the treatment of MC in HIV patients.…”

supporting

confidence: 86%

Complete resolution of facial molluscum contagiosum in a HIV‐infected patient by antiretroviral therapy

Motegi

Sekiguchi

Ishikawa

2017

The Journal of Dermatology

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supporting

confidence: 86%

Complete resolution of facial molluscum contagiosum in a HIV‐infected patient by antiretroviral therapy

Motegi

Sekiguchi

Ishikawa

2017

The Journal of Dermatology

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“…There are case reports where giant molluscum occurring in HIV patients, regressing with HAART [17], combination of HAART and topical imiquimod [18,19], paclitaxel [20].…”

Section: Discussionmentioning

confidence: 99%

Extensive Giant Molluscum Contagiosum in a HIV Positive Patient

Vora

Pilani

Kota

2015

JCDR

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“…These include topical 3% cidofovir cream, photodynamic therapy with 5-aminolevulinic acid, and topical imiquimod. 16–20 Options were restricted in the management of our patient. The absence of well-controlled clinical trials makes treatment of refractory MC challenging, and more research is needed on the epidemiology and therapy of MC-IRIS.…”

Section: Discussionmentioning

confidence: 95%

Recurrent giant molluscum contagiosum immune reconstitution inflammatory syndrome (IRIS) after initiation of antiretroviral therapy in an HIV-infected man

et al. 2013

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Summary We describe an HIV-infected South African male who experienced two distinct episodes of disseminated giant molluscum contagiosum (MC) immune reconstitution inflammatory syndrome (IRIS) over a 6-year period. The first episode of MC-IRIS occurred with rapid virologic suppression following antiretroviral therapy (ART) initiation. The second episode occurred during a rapid increase in CD4 cells following stable viral suppression with second-line ART. His MC lesions then completely resolved during a reduction in CD4 count, despite maintaining virologic suppression. Nearly one year after the resolution of his giant MC-IRIS lesions, he maintains an undetectable viral load, but his level of immune deficiency has not improved. In the absence of well-controlled therapeutic trials, MC-IRIS presents important management challenges.

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Resolution of giantMolluscum contagiosumwith antiretroviral therapy

Cited by 12 publications

References 0 publications

Complete resolution of facial molluscum contagiosum in a HIV‐infected patient by antiretroviral therapy

Complete resolution of facial molluscum contagiosum in a HIV‐infected patient by antiretroviral therapy

Extensive Giant Molluscum Contagiosum in a HIV Positive Patient

Recurrent giant molluscum contagiosum immune reconstitution inflammatory syndrome (IRIS) after initiation of antiretroviral therapy in an HIV-infected man

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