Resorbierbare Implantate in der Unfallchirurgie

Grün, Nicole G.; Donohue, Nicholas; Holweg, Patrick; Weinberg, Annelie‐Martina

doi:10.1007/s41970-018-0041-6

Cited by 4 publications

(1 citation statement)

References 37 publications

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“…Certain groups of materials such as bioactive ceramics are able to accelerate the regeneration of the bone, to stimulate cell proliferation and, at the same time, to degrade and transform themselves into the body’s own material. The advantage of these materials is that no further surgery for the potential removal of parts of the implant is necessary for the patient or no artificial material has to remain in the body, as is the case, for example, with metallic screws, plates or artificial metal, polymer, or ceramic joints [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

Additive Manufacturing of β-Tricalcium Phosphate Components via Fused Deposition of Ceramics (FDC)

et al. 2020

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Bone defects introduced by accidents or diseases are very painful for the patient and their treatment leads to high expenses for the healthcare systems. When a bone defect reaches a critical size, the body is not able to restore this defect by itself. In this case a bone graft is required, either an autologous one taken from the patient or an artificial one made of a bioceramic material such as calcium phosphate. In this study β-tricalcium phosphate (β-TCP) was dispersed in a polymer matrix containing poly(lactic acid) (PLA) and poly(ethylene glycole) (PEG). These compounds were extruded to filaments, which were used for 3D printing of cylindrical scaffolds via Fused Deposition of Ceramics (FDC) technique. After shaping, the printed parts were debindered and sintered. The components combined macro- and micropores with a pore size of 1 mm and 0.01 mm, respectively, which are considered beneficial for bone healing. The compressive strength of sintered cylindrical scaffolds exceeded 72 MPa at an open porosity of 35%. The FDC approach seems promising for manufacturing patient specific bioceramic bone grafts.

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Section: Introductionmentioning

confidence: 99%