Resorption kinetics of osseous substitute: natural coral and synthetic hydroxyapatite

Polycrystalline apatite synthesized by hydrothermal replacement of calcium carbonates

“…The effect of different amounts of porosity in biomaterials has been described in a recent review by Dorozhkin (2010, and references within). There have been reports even of the direct use of coralline calcium carbonates as bone implants which then acted as scaffolds for bone substitution within living organisms, where the amount of resorption depended on the porosity of the implant (Guillemin et al, 1989;Naaman Bou-Abboud et al, 1994;Voigt et al, 1994;Braye et al, 1996;Mü ller-Mai et al, 1996;Vuola et al, 1996). Zaremba et al (1998) suggested that the aragonite-hydroxyapatite conversion in gastropod shell nacre occurs via dissolution-recrystallization.…”

Calcium carbonate–calcium phosphate mixed cement compositions for bone reconstruction

“…Fast-setting CaP bone cements have been studied in depth and developed in the last few years essentially as bone filling and bone reinforcement biomaterials due to their excellent biocompatibility and bioactivity. However, even though they can perfectly fill a bone cavity and be shaped as desired [2][3][4][5][6][7][8][9][10], one of the main concerns of surgeons is to reach higher rates of resorption, an improvement of bone reconstruction and to a lesser extent higher mechanical resistance [11][12][13].…”

A comparison of autogenous bone graft combined with deproteinized bovine bone and autogenous bone graft alone for treatment of alveolar cleft

“…Regarding the non-resorbable property of hydroxyapatite that may retard the bone remodelling process 3,8 , the new bone regenerating within the pores of DBB might be affected by stress shielding and did not undergo mechanical loading, which acted as a trigger for remodelling 1 . In contrast, combining with autogenous bone seems to improve the graft success rate 18 .…”