Facing the challenges of the new industrial revolution, the deep coupling between universities and industry 4.0, the integration of information and communication technologies in education, and the enhancement of the ability to serve society on the basis of internal and external synergy should become the common choice of different types of universities. The university plays an important role in the n development in any advanced economy. In the age of knowledge and globalization rapid technological changes involve new disruptive processes. In this permanent challenge, it is necessary to adapt to the digital transformation, in order to better respond to the needs and challenges of a constantly changing environment. It is necessary to pay attention to technological advances, to a total transformation in the new university, University 4.0, In order to face the challenges of the technological development and the efficiency of universities in Morocco, it is necessary to introduce modern technologies, blockchain technology, artificial intelligence, chatbots..... into the sphere of Moroccan universities.