Respiratory cancer and exposure to man‐made vitreous fibers: A systematic review

Abstract

The results highlight the difficulty of assessing small increases in risk of respiratory cancer potentially caused by occupational exposure in populations with high prevalence of tobacco use.

Risk of lung cancer from exposure to dusts and fibers in Leningrad Province, Russia

“…In our study, male subjects exposed to MMVFs exhibited an increased, though not significant, lung cancer risk. The risks estimated in our study were higher than those reported by a meta-analysis indicating that glass and rock wool exposure is associated with lung cancer [Berrigan, 2002]. We also evaluated whether our findings could have been produced by the presence of asbestos exposure in the same subjects.…”

Occupational Exposure to Rock Wool and Glass Wool and Risk of Cancers of the Lung and the Head and Neck: A Systematic Review and Meta-Analysis

“…These results parallel those of a meta-analysis published in 2002 and other reviews published around the same time. 1,4,15 Because risk estimates in industrybased studies are usually based on comparison with an external population, uncontrolled confounding is virtually impossible to exclude with any level of confidence. 46 Community-based studies of case-control design, on the other hand, are likely to suffer from bias (eg, from selection of cases or controls, retrospective assessment, and absence of validation of exposure), from low-reported prevalence of exposures of interest or jobs related to such exposures, and from residual confounding (eg, by other occupational exposures).…”

“…We retrieved and assessed potentially relevant articles, and checked the lists of references to identify additional candidate studies. We also examined recent reviews 1,4,14,15 for relevant data or information.…”

“…Shortly after the IARC reevaluation, Berrigan 4 performed a meta-analysis of occupational cohort studies and estimated a significant increase in risk of death from respiratory cancer among workers exposed to RW and GW. Several epidemiologic studies have been reported since then, including new results from previously reported cohorts.…”

Manejo de la fibra de vidrio en entorno laboral, potenciales efectos sobre la salud y medidas de control (Revisión)

“…Metaanálisis llevados a cabo por Berrigan y col. (2002) y Lipwort y col. (2009), encontraron un discreto aumento del riesgo para cáncer de pulmón en trabajadores expuestos a lanas de escoria y cáncer de pulmón, aunque en ambos estudios concluyeron que este ligero incremento podía encontrarse más ligado al consumo de tabaco o a exposiciones al amianto de forma independiente o simultánea 45,46 . En resumen, la mayoría de autores consideran que no existe evidencia suficiente para atribuir una asociación causal entre exposición a lanas de vidrio y lanas de roca y el cáncer de pulmón ni para el mesotelioma 47 .…”