“…In addition, in our study the pericardium and the pleurae were opened (both pleurae in one and the left pleura in the other patients), and the results might have been different if the pericardium and the pleurae had been intact. However, when the pericardium and the pleurae are intact, the pleurae produce resistance towards lung expansion as well as the caval veins being exposed to the normal pericardial pressure (29). Thus, theoretically, with intact pleurae and pericardium, the hemodynamic effects of a pulmonary hyperinflation would be even more equal between the open and closed chest conditions than seen in our study.…”
Contrary to our hypothesis, sustained pulmonary hyperinflations with the chest open, i.e. before sternal closure, had similar negative effects on central hemodynamics as those performed with the chest closed, i.e. after sternal closure.
“…In addition, in our study the pericardium and the pleurae were opened (both pleurae in one and the left pleura in the other patients), and the results might have been different if the pericardium and the pleurae had been intact. However, when the pericardium and the pleurae are intact, the pleurae produce resistance towards lung expansion as well as the caval veins being exposed to the normal pericardial pressure (29). Thus, theoretically, with intact pleurae and pericardium, the hemodynamic effects of a pulmonary hyperinflation would be even more equal between the open and closed chest conditions than seen in our study.…”
Contrary to our hypothesis, sustained pulmonary hyperinflations with the chest open, i.e. before sternal closure, had similar negative effects on central hemodynamics as those performed with the chest closed, i.e. after sternal closure.
“…They were able to record concomitant oscillations of esophageal and airway pressures, thus validating esophageal balloon position 38 . Barnas et al have performed abdominal compressions associated to airway occlusion in 13 anesthetized paralyzed patients in the postoperative period of cardiac procedures, validating the balloon technique 39 . A study with 1.5 cm catheter-balloon system positioned in the esophagus at 2-cm intervals has analyzed esophageal pressure along intra-thoracic and cervical segments of healthy humans.…”
Section: Esophageal Balloon Methodsmentioning
confidence: 98%
“…Nesse estudo, puderam ser registradas as oscilações concomitantes das pressões esofágica e de via aérea, validando a posição do balão esofágico 38 . Barnas e col. realizaram compressões abdominais, associadas à oclusão da via aérea em 13 pacientes anestesiados e paralisados no pós-operatório de cirurgia cardíaca, validando a técnica do balão 39 . Estudo realizado utilizando sistema cateter-balão de 1,5 cm, posicionado no esôfago, em intervalos de 2 cm, analisou a pressão esofágica ao longo dos segmentos intratorácicos e cervical em seres humanos saudáveis.…”
The esophageal balloon is the most common method to obtain indirect pleural pressure. In sedated or anesthetized patients without major respiratory compliance changes, esophageal pressure variation corresponds to pleural pressure variation when PEEP is applied.
“…Numerous reports describe the association between the surgical technique and changes in respiratory mechanics and lung function [22,[29][30][31][32][33] . Median sternotomy disrupts sternum integrity, provokes chest wall instability (i.e., uncoordinated rib cage expansion, decrease compliance), and reduces lung volumes with subsequent impaired pulmonary mechanics [29,31] .…”
Section: Sternotomy Incision Sternosynthesis and Left Internal Mammmentioning
Postoperative pulmonary dysfunction is a multifactorial complication in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Numerous risk factors including individual, surgery-and anesthesia-related have been identified. Exacerbated systemic and pulmonary inflammatory response to CPB is one of the most studied mechanisms of lung injury in this patient setting. However, current literature lacks specific intraoperative mechanical ventilation (MV) strategies associated with a significant improvement in patients' outcomes. We reviewed the randomized clinical trials and other reports published within the last 5 years involving patients undergoing cardiac surgery with CPB in order to summarize the existing MV strategies used in these patients and their associated outcomes. Moreover, we described the pathophysiological mechanisms involved in post-CPB lung injury and the mechanistic effects of protective ventilation.
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