Respiratory presentations to acute services at a tertiary hospital in South Africa

Ngah, Vera; Maud, P; Baines, Nicola; Mistry, Rahul; Schrueder, Neshaad; Koegelenberg, C F N; Irusen, Elvis; Mortimer, Kevin; Allwood, Brian

doi:10.7196/samj.2021.v111i11.15711

Cited by 4 publications

(4 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In a South African study including 1,053 patients presenting with a primary respiratory diagnosis to an acute service at a tertiary hospital in Cape Town, hemoptysis was seen in 10% of patients, mainly related to PTLD (38%) and pulmonary TB (37%). 79 In a recent cross-sectional study in an urban tertiary hospital in Sierra Leone, current or past TB infection (odds ratio: 3.52) was an independent predictor of Aspergillus seropositivity and CPA. 80 Risk factors for CPA in patients with active TB are age > 40 years, smoking, diabetes, low body mass index, male sex, steroid use, and cavitary disease.…”

Section: Clinical Presentation Of Chronic Pulmonary Aspergillosis In ...mentioning

confidence: 94%

Chronic Pulmonary Aspergillosis as a Considerable Complication in Post-Tuberculosis Lung Disease

Neuböck,

Günther,

Barac

et al. 2024

Semin Respir Crit Care Med

View full text Add to dashboard Cite

Post-tuberculosis lung disease (PTLD) has only recently been put in the spotlight as a medical entity. Recent data suggest that up to 50% of tuberculosis (TB) patients are left with PTLD-related impairment after completion of TB treatment. The presence of residual cavities in the lung is the largest risk factor for the development of chronic pulmonary aspergillosis (CPA) globally. Diagnosis of CPA is based on four criteria including a typical radiological pattern, evidence of Aspergillus species, exclusion of alternative diagnosis, and a chronic course of disease. In this manuscript, we provide a narrative review on CPA as a serious complication for patients with PTLD.

show abstract

Section: Clinical Presentation Of Chronic Pulmonary Aspergillosis In ...mentioning

confidence: 94%

Chronic Pulmonary Aspergillosis as a Considerable Complication in Post-Tuberculosis Lung Disease

Neuböck,

Günther,

Barac

et al. 2024

Semin Respir Crit Care Med

View full text Add to dashboard Cite

show abstract

“…[2] South Africa (SA) has an extremely high prevalence of pulmonary TB, in excess of 1 000/100 000 in some subpopulations, and consequently a high burden of TB-related haemoptysis. [3,4] Haemoptysis can occur during active TB infection, or as a sequel of previous TB infection, and may present as either trivial or life threatening. PA involvement is a risk factor for death in haemoptysis, and it is thought that between 5% and 10% of cases of life-threatening haemoptysis arise from the pulmonary arterial system.…”

Section: In Practicementioning

confidence: 99%

“…The patients in this report were treated at Tygerberg Hospital, a tertiary referral centre in Cape Town, SA, in which 9.8% of acute respiratory admissions are for haemoptysis. [4] Between November 2018 and June 2021, patients referred for the management of life-threatening haemoptysis (defined as haemoptysis causing haemodynamic instability, or a drop in measured haemoglobin, the need for blood transfusion, respiratory support for haemorrhage-related hypoxaemia, or witnessed expectoration of >500 mL in 24 hours) underwent chest computed tomography pulmonary angiogram (CTPA) once clinically stabilised. A CTPA was performed with a Somatom Definition Edge TM 128 MDCT (Siemens, Germany).…”

Section: Case Seriesmentioning

confidence: 99%

Issues in Medicine

Shaw

John²,

Koegelenberg³

et al. 2023

S Afr Med J

Self Cite

View full text Add to dashboard Cite

Rasmussen aneurysms are abnormalities of the pulmonary arterial system caused by tuberculosis (TB). They are associated with a highmortality rate when they cause life-threatening haemoptysis. High TB-prevalence regions have a large burden of TB-related haemoptysisbut often limited resources. This series of 25 patients who presented with life-threatening haemoptysis from current and/or previous TBwere found to have abnormal pulmonary arteries on computed tomography pulmonary angiogram (CTPA), which were judged to belikely contributors to their bleeding, either in isolation or with concomitant abnormal bronchial or systemic vasculature. These patientsunderwent transcatheter placement of Amplatzer vascular plugs in the feeder pulmonary artery. Bronchial and systemic lesions wereaddressed separately as needed. Immediate technical success was achieved in all patients, but four of them experienced intraoperativehaemoptysis related to dislodgement of the occluding platelet plug by the high-pressure automatic injector and wire. At 48 hours after theprocedure, 18 (72%) remained haemoptysis-free. Six of these experienced recurrence within 1 year of their procedure. Pulmonary arteryplacement of an Amplatzer vascular plug is a feasible option for treating bleeding Rasmussen aneurysms, but should be part of a combinedapproach to addressing suspected culprit vascular lesions in all intrathoracic vascular systems.

show abstract

“…Chronic respiratory diseases (CRDs), as the most common non-communicable diseases, are prevalent worldwide and affect both developed and developing countries ( 1 ), Research showed that CRDs are accounting for >10% of the global burden of disease ( 2 ), and in 2017, about 545 million people across the world had a CRD, among which global prevalence of chronic obstructive pulmonary disease (COPD) and asthma were 3.9 and 3.6%, respectively ( 3 ). In 2020, there were about 2.2 million new lung cancer cases and 1.8 million deaths worldwide ( 4 ).…”

Section: Introductionmentioning

confidence: 99%

Research Trends on Pulmonary Rehabilitation: A Bibliometric Analysis From 2011 to 2020

Chen

2022

Front. Med.

View full text Add to dashboard Cite

Background and ObjectiveA mounting body of evidence suggests that lung function may deteriorate over time with the development of chronic lung diseases (CRDs). Pulmonary rehabilitation has been proved to improve exercise capacity and quality of life in individuals with CRDs. However, PR remains grossly underutilized all around the world. This study aimed to analyze the research trends on PR over the past 10 years.MethodsThe publications related to pulmonary rehabilitation in the Web of Science Core Collection (WoSCC) from 2011 to 2020 were searched. VOSviewer (1.6.15) and CiteSpace Software (5.5.R2) were used to analyze authors and co-cited authors, countries and institutions, journals and co-cited journals, co-cited references, and keywords.ResultsA total of 4,521 publications were retrieved between 2011 and 2020, and the number of annual publications on pulmonary rehabilitation has shown an overall upward trend in the past decade. The USA was the most productive country, the University of Toronto from Canada was both the first in publications and citations. Spruit MA was both the most productive author and the one with the highest number of co-citations. The first productive journal was the International Journal of Chronic Obstructive Pulmonary Disease, while the first co-cited journal was the American Journal of Respiratory and Critical Care Medicine. The hot keywords were grouped into three clusters, while “Asthma” and “Respiratory society statement” were determined as the frontier topics.ConclusionsThe present study successfully revealed the research status and development trends of pulmonary rehabilitation from 2011 to 2020 by using bibliometric analysis, which may help researchers explore and discover new research directions in the future.

show abstract

Respiratory presentations to acute services at a tertiary hospital in South Africa

Cited by 4 publications

References 19 publications

Chronic Pulmonary Aspergillosis as a Considerable Complication in Post-Tuberculosis Lung Disease

Chronic Pulmonary Aspergillosis as a Considerable Complication in Post-Tuberculosis Lung Disease

Issues in Medicine

Research Trends on Pulmonary Rehabilitation: A Bibliometric Analysis From 2011 to 2020

Contact Info

Product

Resources

About