Respiratory System

Cox, John

doi:10.1007/978-1-4471-3304-9_8

Cited by 4 publications

(1 citation statement)

References 521 publications

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“…Abnormalities of the lung itself such as malformation, growth failure or functional immaturity may impair or prevent establishment of extrauterine existence or life may b e threatened by asphyxia, haemorrhage and infection. As the pathology of the lung in the perinatal period is covered in general terms in a number of texts (Larroche 1977, Cox 1981, Wigglesworth 1984 it is proposed in this review to concentrate on problems of growth and maturation of the organogenetically normal lung and on the manifestations of hyaline membrane disease.…”

Section: Introductionmentioning

confidence: 99%

Pathology of the lung in the fetus and neonate, with particular reference to problems of growth and maturation

Wigglesworth

1987

Histopathology

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The major forms of lung pathology in the perinatal period are reviewed with emphasis on disturbances of growth and maturation. Lung hypoplasia results from impairment in the physiological control of lung growth during the fetal period. It is more common than organogenetic defects which are discussed only briefly. Hyaline membrane disease is now seldom seen in a pure form due to improvements in perinatal care. However, its complications and sequelae such as interstitial emphysema, pneumothorax and bronchopulmonary dysplasia are encountered more frequently. In addition, a wide variety of pathological processes may localize to, or be expressed in, the lung of the newborn, notably asphyxial changes, persistent pulmonary hypertension, haemorrhage and infection.

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Section: Introductionmentioning

confidence: 99%

Pathology of the lung in the fetus and neonate, with particular reference to problems of growth and maturation

Wigglesworth

1987

Histopathology

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Squamous cell carcinoma of the trachea in an infant: a case report

Contencin

Cortez

et al. 1998

International Journal of Pediatric Otorhinolaryngology

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Generalized neonatal herpes virus infection (cytomegalovirus or herpes virus type 1) comparative examination of loci attacked by two viruses^3,⁴

Watanabe

Tanaka

Hatano

et al. 1984

Acta Pathologica Japonica

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Two autopsy cases, a 5-minute-old male infant with congenital cytomegalovlrus (CMV) infection and a 10-day-old female infant with herpes simplex virus type 1 (IISV-1) infection, were presented. CMV antibody titer detectable by immunofluorescence (IF) technique was significantly high in the sera of both Infant and mother in the CMV case. In another HSV-1 case, we have succeeded in HSV-1 isolation from autopsy liver and subsequent serological identification of the isolated virus, including a detection of high HSV-1 antibody titer in the mother's serum by IF. On light and electron microscopes, these two cases respectively showed typical findings as the severest form of each viral Infection. As one of the marked differences between the two cases, the thymus in the IISV-1 case showed remarkable involution with a complete disappearance of thymic cortical lymphocytes. However, the CMV case exhibited an existence of Intact thymus without viral injuries. Similar dlstinguishable differences between the two cases were observed also In the bone marrow. It additionally seems to be unique that cytomegalic inclusion bodies were disclosed fairly well in the submaxillary glands and rarely in the renal tubules even In the case with Case Reports Case 1. A male infant after 31 week's gestation was delivered to a 26-year-old primigravida by Caesarian section because of earlier rupture of fetal membrane and prolapse of cord caused by breech presentation. The infant was mildly asphyxia1 a t birth and had Apgar score 5, but soon after he became worse and died in 5 minutes in spite of resuscitative efforts. The mother had been uneventful during pregnancy except for slight fever of 37.5"~ a t 8 weeks' gestation. 34(4): 1984K WATANABE el 01. 849

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Respiratory System

Cited by 4 publications

References 521 publications

Pathology of the lung in the fetus and neonate, with particular reference to problems of growth and maturation

Pathology of the lung in the fetus and neonate, with particular reference to problems of growth and maturation

Squamous cell carcinoma of the trachea in an infant: a case report

Generalized neonatal herpes virus infection (cytomegalovirus or herpes virus type 1) comparative examination of loci attacked by two viruses^3,⁴

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Respiratory System

Cited by 4 publications

References 521 publications

Pathology of the lung in the fetus and neonate, with particular reference to problems of growth and maturation

Pathology of the lung in the fetus and neonate, with particular reference to problems of growth and maturation

Squamous cell carcinoma of the trachea in an infant: a case report

Generalized neonatal herpes virus infection (cytomegalovirus or herpes virus type 1) comparative examination of loci attacked by two viruses3,4

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Generalized neonatal herpes virus infection (cytomegalovirus or herpes virus type 1) comparative examination of loci attacked by two viruses^3,⁴