Respon Imun Ayam Petelur Pascavaksinasi Newcastle Disease Pada Peternakan Komersial Di Desa Denbantas, Kecamatan Tabanan

Suwartini, Ni Komang; Kencana, Gusti Ayu Yuniati; Suartha, I.N.

doi:10.19087/imv.2018.7.3.185

Cited by 2 publications

(2 citation statements)

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“…The titers of secondary antibodies are greater than those of the primary immune response. This is due to the fact that memory cells generated during the primary immune response endure rapid transformation and differentiation into antibody-producing cells (Suwartini et al, 2018).…”

Section: Resultsmentioning

confidence: 99%

Immunomodulatory Activity of Kasumba Turate (Carthamus tinctorius L.) Extract Against Non-Specific and Specific Immune Responses in Mice

Fadhilah,

Parwati,

Muflihah

et al. 2023

Pharmacon

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Immunomodulators are compounds that can regulate the immune system with the objective of normalizing or helping to optimize the immune system. People tend to back to nature by utilizing various plants to be used as medicine, one of which is kasumba turate (Carthamus tinctorius L.) which is thought to be efficacious as an immunomodulator in increasing the activity and capacity of macrophages. This study aims to determine the immunomodulatory activity of kasumba turate ethanol (CTEE) extract against non-specific and specific immune responses in mice. Non-specific immune response tests using the carbon clearance method were carried out on mice with 3 dose ratings. Specific immune response tests were carried out by the hemagglutination test method to determine antibody titers. The results of the carbon clearance test showed that the CTEE dose 50 mg/KgBW was a moderate immunostimulant with a phagocytic index of 1.41, while doses of 100 and 200 mg/KgBW were strong immunostimulants with phagocytic index of 1.57 and 1.82 respectively. While the results of the hemagglutination test method, the antibody titers value is determined from the highest serum dilution value that still indicates hemagglutination. The results show an increase in humoral immune response with the highest primary and secondary antibody titer values of 1:256 and 1:1024 for doses of 100 mg/KgBW, and 1:512 and 1:1024 for doses of 200 mg/KgBW. Phytochemical screening results of CTEE proved to contain alkaloid group compounds, flavonoids, saponins, tannins and triterpenoids. Based on the results obtained, it was concluded that the administration of CTEE showed immunostimulant activity.

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Section: Resultsmentioning

confidence: 99%

Immunomodulatory Activity of Kasumba Turate (Carthamus tinctorius L.) Extract Against Non-Specific and Specific Immune Responses in Mice

Fadhilah,

Parwati,

Muflihah

et al. 2023

Pharmacon

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“…Respon kekebalan sekunder mampu menghasilkan titer antibodi dan afinitas yang lebih tinggi serta fase lag yang terjadi lebih pendek dibandingkan dengan respon imun primer. Hal ini disebabkan karena adanya sel memori yang terbentuk dari paparan virus yang pertama, akan cepat mengalami transformasi dan berdiferensiasi menjadi sel penghasil antibodi (Suwartini et al, 2018).…”

Section: Pembahasanunclassified

Deteksi Titer Antibodi Newcastle Disease pada Broiler yang Divaksinasi di Pembibitan Umur Satu Hari

Arnaya

Suardana

Nindhia

2023

bulvet

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Vaksinasi saat antibodi maternal masih tinggi menyebabkan reaksi netralisasi antibodi sehingga respon kekebalan yang dihasilkan tidak optimal. Pengukuran titer antibodi pascavaksinasi merupakan indikator dalam menilai keberhasilan vaksinasi dan dapat diuji dengan serologis Hemagglutination Inhibition. Penelitian ini bertujuan untuk mengetahui hingga umur berapa titer antibodi seropositif pada broiler yang divaksinasi di pembibitan umur satu hari. Data diperoleh dengan cara pengambilan sampel secara acak dari populasi broiler yang diambil sebanyak 4 kali pada hari ke-7, ke-14, ke-21 dan ke-28. Data yang diperoleh di analisis menggunakan metode Analysis of Variance, kemudian dilanjutkan dengan analisis regresi. Hasil penelitian menunjukkan bahwa broiler yang divaksinasi di pembibitan umur satu hari menghasilkan titer seropositif hingga umur 13 hari dengan titer 4,2 HI log 2 dan mulai mengalami penurunan di umur 14 hari yaitu 3,9 HI log 2. Kesimpulan dari penelitian ini yaitu broiler yang divaksinasi di pembibitan umur satu hari menghasilkan titer seropositif hingga umur 13 hari. Saran perlu dilakukan vaksinasi booster di umur 13 hari pada broiler yang divaksinasi di pembibitan umur satu hari.

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Respon Imun Ayam Petelur Pascavaksinasi Newcastle Disease Pada Peternakan Komersial Di Desa Denbantas, Kecamatan Tabanan

Cited by 2 publications

References 0 publications

Immunomodulatory Activity of Kasumba Turate (Carthamus tinctorius L.) Extract Against Non-Specific and Specific Immune Responses in Mice

Immunomodulatory Activity of Kasumba Turate (Carthamus tinctorius L.) Extract Against Non-Specific and Specific Immune Responses in Mice

Deteksi Titer Antibodi Newcastle Disease pada Broiler yang Divaksinasi di Pembibitan Umur Satu Hari

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